Vorschaubild nicht verfügbar
Publikationstyp
Conference proceedings
Monographie
Monographie
Erscheinungsjahr
2014
DOI
Harmonisation of QA/QC measures among large-scale children's environmental studies
Harmonisation of QA/QC measures among large-scale children's environmental studies
Autor:innen
Herausgeber
Quelle
24th annual meeting of International Society of Exposure Science
Schlagwörter
Forschungskennzahl (FKZ)
Verbundene Publikation
Zitation
Harmonisation of QA/QC measures among large-scale children’s environmental studies, 2014. [online]. Verfügbar unter: https://openumwelt.de/handle/123456789/8569
Zusammenfassung englisch
There is mounting interest in the impact of the environment on childrens health and development.
Recently, large-scale studies of childrens environmental health, including both longitudinal and cross-sectionaldesigns, have been planned and implemented in several countries. These studies, aiming to better understandhow social, environmental and genetic factors affect childrens health, put special emphasis on the effect ofenvironmental stressors. Among a wide range of environmental stressors, the effect of chemical contaminants isone of the focus areas to be investigated. In order to examine the relationship between chemical exposure andchildrens health in longitudinal studies, individual exposure estimation is required rather than generalinformation on the exposure of the population. Exposure assessment utilizes monitoring, modelling andquestionnaires. Among these, biological monitoring (human biomonitoring) is one of the most powerful methodsto investigate individual exposure to chemical contaminants. However, different studies employ differentmeasurement methods, which hampers future data pooling and analysis among the studies. France, Germany,Japan, Shanghai (China) and the United States that are planning or conducting large-scale childrensenvironmental health studies have gathered to form an international working group to harmonize outcome andexposure measurement methodologies. The group identified three major contaminants including mercury,236phthalates and organophosphates for the first step of the harmonization. The group started sharing informationabout sample collection, analytical methods, quality assurance procedures and data reporting formats for thethree contaminants. Round-robin trials have also been conducted to identify key issues for furtherharmonization. The progress of the working group discussion and trials will be presented in the symposium.Acknowledgement: Environment and Childrens Health International Birth Cohort Group.
Quelle: 24th Annual Meeting ofThe International Society of Exposure Science: Exposure Science Integration to Protect Ecological Systems,Human Well-Being, and Occupational Health; Abstract Book ISES 2014 / International Society of Exposure Science, Cincinnati: 2014, S.235-236
Recently, large-scale studies of childrens environmental health, including both longitudinal and cross-sectionaldesigns, have been planned and implemented in several countries. These studies, aiming to better understandhow social, environmental and genetic factors affect childrens health, put special emphasis on the effect ofenvironmental stressors. Among a wide range of environmental stressors, the effect of chemical contaminants isone of the focus areas to be investigated. In order to examine the relationship between chemical exposure andchildrens health in longitudinal studies, individual exposure estimation is required rather than generalinformation on the exposure of the population. Exposure assessment utilizes monitoring, modelling andquestionnaires. Among these, biological monitoring (human biomonitoring) is one of the most powerful methodsto investigate individual exposure to chemical contaminants. However, different studies employ differentmeasurement methods, which hampers future data pooling and analysis among the studies. France, Germany,Japan, Shanghai (China) and the United States that are planning or conducting large-scale childrensenvironmental health studies have gathered to form an international working group to harmonize outcome andexposure measurement methodologies. The group identified three major contaminants including mercury,236phthalates and organophosphates for the first step of the harmonization. The group started sharing informationabout sample collection, analytical methods, quality assurance procedures and data reporting formats for thethree contaminants. Round-robin trials have also been conducted to identify key issues for furtherharmonization. The progress of the working group discussion and trials will be presented in the symposium.Acknowledgement: Environment and Childrens Health International Birth Cohort Group.
Quelle: 24th Annual Meeting ofThe International Society of Exposure Science: Exposure Science Integration to Protect Ecological Systems,Human Well-Being, and Occupational Health; Abstract Book ISES 2014 / International Society of Exposure Science, Cincinnati: 2014, S.235-236