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Publikationstyp
Conference proceedings
Monographie
Monographie
Erscheinungsjahr
2016
DOI
Introducing the Cooperation for the Promotion of Human Biomonitoring
Introducing the Cooperation for the Promotion of Human Biomonitoring
Autor:innen
Herausgeber
Quelle
26th Annual Meeting of the International Society of Exposure Science (26 : 2016 : Utrecht)
Schlagwörter
Zitation
Introducing the Cooperation for the Promotion of Human Biomonitoring, 2016. [online]. Utrecht. Verfügbar unter: https://openumwelt.de/handle/123456789/7072
Zusammenfassung englisch
Introduction: Human biomonitoring (HBM) yields sound data on the human exposure to chemicals. Thus, HBM provides information on the need for further action in policy-making or the sufficiency of already applied regulation. HBM also supports the identification of population subgroups that are higher exposed than others and therefore need increased attention in environmental health and consumer protection. Methods: A joint project for increasing the knowledge on chemicals taken up by people from manifold sources and for further improving HBM by developing new analytical methods was started by the German Federal Ministry for the Environment, Nature Conservation, Building and Nuclear Safety (BMUB) and the German Chemical Industry Association (VCI) in 2010. The German Environment Agency (UBA) supports this cooperation by scientific counseling and leading the head office. The cooperation focuses on substances either with potential health-relevance and/or for which an exposure of the general population can be assumed. For many chemicals falling into this category, currently no analytical method for human samples (e. g. urine or blood) exists that allows a specific and sensitive detection of environmental exposure. Hence, a main goal of the cooperation is to develop reliable biomonitoring methods for up to 50 substances by 2020. All these methods will be cross-validated by the independent expert-working group "Analyses in biological Materials" of the German Research Foundation (DFG). VCI is responsible for the development of the methods. This often includes metabolism studies to identify the relevant biomarkers. UBA supports BMUB in the application of the methods, usually within the framework of the German Environmental Specimen Bank (ESB) and the German Environmental Surveys (GerES). Additionally, the German Human Biomonitoring Commission derives human biomonitoring assessment values for the selected chemicals. Results: Since 2010, methods for 14 chemicals have been developed, including i. a. plasticizers, flame retardants, and technical solvents. The most current methods developed are for the preserving additive CIT/MIT, the plasticizer DEHTP, the antioxidant BHT, and the fragrance Lysmeral. In 2016 method development started for the flame retardant TDCP, the UV filters Uvinul A Plus and Avobenzon, the plasticizer DBA, and the fuel additive Keromet MD. All in all 34 methods have been selected for method development so far. The current status of method development, an overview on scientific articles on methods already available, and envisaged future methods are available on the UBA website. Conclusions: To reach the envisaged number of selected substances for method development of 50 within 10 years, up to 16 more substances will be selected. The cooperation demonstrates that the ongoing development of new analytical methods is vital for fully utilizing HBM̷s potential for environmental health and consumer protection. In view of the large variety of chemicals available on the market, human exposure assessment by HBM strongly depends on the number of sound analytical methods available and their ongoing application in population studies. References: UBA 2016, Cooperation for the promotion of human biomonitoring. https://www.umweltbundesamt.de/en/topics/health/assessing-environmentally-related-health-risks/human-biomonitoring/cooperation-for-the-promotion-of-human In: In: Abstract Book / International Society of Exposure Science - Annual Meeting : interdisciplinary approaches for health and the environment ; Utrecht, the Netherlands, october 9-13. Utrecht: 2016, Seite 708-709