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Publikationstyp
Wissenschaftlicher Artikel
Erscheinungsjahr
2021
Environmental substances associated with osteoporosis - a scoping review
Environmental substances associated with osteoporosis - a scoping review
Autor:innen
Herausgeber
Quelle
International Journal of Environmental Research and Public Health
18 (2021), Heft 2
18 (2021), Heft 2
Schlagwörter
Zitation
ELONHEIMO, Hanna, Marike KOLOSSA-GEHRING, Hanna TOLONEN und Rosa LANGE, 2021. Environmental substances associated with osteoporosis - a scoping review. International Journal of Environmental Research and Public Health [online]. 2021. Bd. 18 (2021), Heft 2. DOI 10.60810/openumwelt-877. Verfügbar unter: https://openumwelt.de/handle/123456789/3389
Zusammenfassung englisch
Introduction: Osteoporosis is a disease having adverse effects on bone health and causing fragility fractures. Osteoporosis affects approximately 200 million people worldwide, and nearly 9 million fractures occur annually. Evidence exists that, in addition to traditional risk factors, certain environmental substances may increase the risk of osteoporosis. Methods: The European Human Biomonitoring Initiative (HBM4EU) is a joint program coordinating and advancing human biomonitoring in Europe. HBM4EU investigates citizens' exposure to several environmental substances and their plausible health effects aiming to contribute to policymaking. In HBM4EU, 18 priority substances or substance groups were selected. For each, a scoping document was prepared summarizing existing knowledge and health effects. This scoping review is based on these chemical-specific scoping documents and complementary literature review. Results: A possible link between osteoporosis and the body burden of heavy metals, such as cadmium (Cd) and lead (Pb), and industrial chemicals such as phthalates and per- and poly-fluoroalkyl substances (PFASs) was identified. Conclusions: Evidence shows that environmental substances may be related to osteoporosis as an adverse health effect. Nevertheless, more epidemiological research on the relationship between health effects and exposure to these chemicals is needed. Study results are incoherent, and pervasive epidemiological studies regarding the chemical exposure are lacking. © 2021 by the authors