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Publikationstyp
Wissenschaftlicher Artikel
Erscheinungsjahr
Autor:innen
Herausgeber
Quelle
International Journal of Hygiene and Environmental Health
248 (2023), Heft 114097
248 (2023), Heft 114097
Schlagwörter
Human-Biomonitoring, Gesundheitsgefährdung
Förderkennzeichen (FKZ)
Forschungskennzahl
Verbundene Publikation
Zitation
Human biomonitoring guidance values (HBM-GVs) for priority substances under the HBM4EU initiative - new values derivation for deltamethrin and cyfluthrin and overall results. (2023). International Journal of Hygiene and Environmental Health, 248 (2023), Heft 114097. https://doi.org/10.60810/openumwelt-1864
Zusammenfassung englisch
The European Initiative HBM4EU aimed to further establish human biomonitoring across Europe as an important tool for determining population exposure to chemicals and as part of health-related risk assessments, thus making it applicable for policy advice. Not only should analytical methods and survey design be harmonized and quality assured, but also the evaluation of human biomonitoring data. For the health-related interpretation of the data within HBM4EU, a strategy for deriving health-based human biomonitoring guidance values (HBM-GVs) for both the general population and workers was agreed on. On this basis, HBM-GVs for exposure biomarkers of 1,2-cyclohexane dicarboxylic acid diisononyl ester (DINCH), phthalates (diethyl hexyl phthalate (DEHP), di-n-butyl phthalate (DnBP), diisobutyl phthalate (DiBP), butyl benzyl phthalate (BBzP), and bis-(2-propylheptyl) phthalate (DPHP)), bisphenols A and S, pyrethroids (deltamethrin and cyfluthrin), solvents (1-methyl-2-pyrrolidone (NMP), 1-ethylpyrrolidin-2-one (NEP), N-dimethylformamide (DMF), N,N-dimethylacetamide (DMAC)), the heavy metal cadmium and the mycotoxin deoxynivalenol (DON) were developed and assigned a level of confidence. The approach to HBM-GV derivations, results, and limitations in data interpretation with special focus on the pyrethroids are presented in this paper. © 2023 The Authors