Publikation:
Comparing pharmaceutical persistence across terrestrial and aquatic environments: do studies according to OECD 307 and OECD 308 lead to similar outcomes?

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dc.contributor.authorBerkner, Silvia
dc.contributor.authorBrandt, Ute
dc.date.accessioned2024-06-16T12:43:13Z
dc.date.available2024-06-16T12:43:13Z
dc.date.issued2023
dc.description.abstractInformation on transformation and persistence of chemical substances in the environment is important for hazard and risk assessment within a regulatory context or as a decision criterion in a safe and sustainable by design framework. Half-lives for human and veterinary medicinal products available from marketing authorization applications were compared between soil (OECD 307) and aquatic water/sediment systems (OECD 308). The comparison shows, that there is no obvious correlation between the total system half-lives in the two different compartments and that surpassing persistence criteria is compartment-specific in 45% of the cases. © The Author(s) 2023en
dc.format.extent1 Onlineresource (4 pages)
dc.format.mediumonline resource
dc.identifier.doihttps://doi.org/10.60810/openumwelt-2180
dc.identifier.urihttps://openumwelt.de/handle/123456789/1679
dc.language.isoeng
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/
dc.subjectPersistenz
dc.titleComparing pharmaceutical persistence across terrestrial and aquatic environments: do studies according to OECD 307 and OECD 308 lead to similar outcomes?
dc.typeWissenschaftlicher Artikel
dc.type.dcmitext
dc.type.mediumcomputer
dspace.entity.typePublication
local.bibliographicCitation.journalTitleEnvironmental Sciences Europe
local.bibliographicCitation.originalDOI10.1186/s12302-023-00783-8
local.bibliographicCitation.volume35 (2023)
local.collectionAufsätze
local.contributor.authorId02143078
local.contributor.authorId02145596
local.identifier.catalogId02500285
local.ingest.leader04027naa a2200000uu 4500
local.jointTitleCOMPARING PHARMACEUTICAL PERSISTENCE ACROSS TERRESTRIAL AND AQUATIC ENVIRONMENTS DO STUDIES ACCORDING TO OECD 307 AND OECD 308 LEAD TO SIMILAR OUTCOMES
local.reviewtrue
local.sourcecatalog
local.source.urihttp://creativecommons.org/licenses/by/4.0/deed.de
local.staffPublicationtrue
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