Publikation:
Sharing experiences from human biomonitoring studies and programs in Germany and Europe

Kurzanzeige
dc.contributor.otherKolossa-Gehring, Marike
dc.contributor.otherApel, Petra
dc.contributor.otherFiddicke, Ulrike
dc.contributor.otherSchwedler, Gerda
dc.contributor.otherConrad, André
dc.date.accessioned2024-06-16T16:01:45Z
dc.date.available2024-06-16T16:01:45Z
dc.date.issued2015
dc.description.abstractThe Health Research Framework Program of the German Federal Government identifies birth cohorts as the instrument of choice to elucidate relationships between exposure to environmental chemicals, well-being of infants and children, and health in later life. But even large scale birth cohorts can for practical reasons - sample collection, burden of participants, and costs - not cover all issues of concern. Therefore, integrating experiences from other national and international studies is necessary for setting priorities in the study design, e.g. selection of chemicals to be analyzed. Lessons learned from German and European HBM studies and programs may support this process: 1) Focusing on health relevance and potential exposure of the general population, the scientific agencies in charge of chemical safety in Germany have identified emerging chemicals and assigned high priority to them for being analyzed in population studies. 2) Observed links between chemicals (e.g. fragrances) and health effects in cross-sectional studies further predestine compounds for evaluation in cohort studies. 3) Availability of assessment values is also important when choosing biomarkers: UBAs Human Biomonitoring Commission has derived 6 new toxicologically based HBM values to assess internal exposures. First HBM data on the solvents N-ethyl-2-pyrrolidone and N-methyl-pyrrolidone and the new plasticizer Hexamoll® DINCH and di-2-propylheptyl phthalate (DPHP) show that exposures are well below the specific HBM-I-values. 4) Options for combining data from several international studies may be another reason for decisions on study design. For joint data assessment, transfer of (individual) data and exchange of samples, ethical and data protection standards have to be considered. Experiences from the German Environmental Survey (GerES), the German Environmental Specimen Bank (ESB) and the European HBM project COPHES help solving these issues also in birth cohorts.Quelle: 25th annual meeting of the International Society of Exposure Science (ISES). 18-22 October 2015. Henderson-Nevada USA. URL: http://www.ises2015.org/. We-S-B1-02.S. 179.en
dc.format.extent14 Vortragsfolien
dc.format.extentIll., graph. Darst.
dc.identifier.urihttps://openumwelt.de/handle/123456789/7731
dc.language.isoeng
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/
dc.subjectBiomonitoring
dc.subjectEpidemiologie
dc.titleSharing experiences from human biomonitoring studies and programs in Germany and Europe
dc.typeConference proceedings
dc.typeMonographie
dspace.entity.typePublication
local.bibliographicCitation.conference25th annual meeting of the International Society of Exposure Science (ISES)
local.collectionRede
local.contributor.otherId(DE-588)1084188597
local.contributor.otherId00400713
local.contributor.otherId(DE-588)18159966X
local.contributor.otherId02054215
local.contributor.otherId02146005
local.contributor.otherId02146006
local.contributor.otherId02114611
local.identifier.catalogId02431293
local.ingest.leader05465nam a2200000uu 4500
local.jointTitleSHARING EXPERIENCES FROM HUMAN BIOMONITORING STUDIES AND PROGRAMS IN GERMANY AND EUROPE
local.sourcecatalog
local.staffPublicationtrue
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