Low dose effects and non-monotonic dose responses for endocrine active chemicals: Science to practice workshop: Workshop summary

Abstract

A workshop was held in Berlin September 12-14th 2012 to assess the state of the science of the data supporting<BR>low dose effects and non-monotonic dose responses (´´low dose hypothesis) for chemicals with<BR>endocrine activity (endocrine disrupting chemicals or EDCs). This workshop consisted of lectures to present<BR>the current state of the science of EDC action and also the risk assessment process. These lectures<BR>were followed by breakout sessions to integrate scientists from various backgrounds to discuss in an<BR>open and unbiased manner the data supporting the ´´low dose hypothesis. While no consensus was<BR>reached the robust discussions were helpful to inform both basic scientists and risk assessors on all<BR>the issues. There were a number of important ideas developed to help continue the discussion and<BR>improve communication over the next few years.<BR>Quelle: 2013 The Authors. Published by Elsevier Ltd. All rights reserved.