Publikation:
Harmonization of environmental exposure assessment for veterinary pharmaceuticals and biocides

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dc.contributor.authorDüring, Rolf-Alexander
dc.contributor.authorWohde, Manuel
dc.contributor.authorJunker, Thomas
dc.contributor.organisationOtherECT Oekotoxikologie GmbH (Flörsheim am Main)
dc.contributor.organisationOtherFraunhofer-Institut für Molekularbiologie und Angewandte Oekologie
dc.contributor.organisationalEditorDeutschland. Umweltbundesamt
dc.contributor.otherBerkner, Silvia
dc.contributor.otherKonradi, Sabine
dc.date.accessioned2024-06-16T15:19:56Z
dc.date.available2024-06-16T15:19:56Z
dc.date.issued2016
dc.date.submittedStand: March 2016
dc.description.abstractThe spread of veterinary medicinal products (VMPs) and biocides onto agriculturally used areas represents a very important path of entry into the environment for these product groups. Within this literature study public available transformation studies with liquid manure are summarized. Transformation studies were evaluated considering the transformation fate of tested substances, the origin and characteristics of used manure, the experimental setup, the measured parameters and the main outcome of the studies. Test duration throughout the studies ranges from 2 to 374 days and study temperature ranges from 5 °C to 55 °C. As main topics within the 34 found transformation studies the high dependency of transformation on temperature, redox potential, dry matter content and many other parameters is reported. It was further critically analyzed which basic information and parameters were neglected. Unfortunately only six publications give information on the redox potential of the manure. Further, the characterization of the matrix in many cases is inadequate due to missing parameters such as dry matter content, pH, and TOC.Additionally, public available monitoring data of VMPs in manure were collected and evaluated regarding the origin and characteristics of the manure, the minimum and maximum found concentrations, and percentage of identified compounds. Within the 27 found publications, 1568 manure samples were analyzed and 39 different active substances for VMPs and 11 metabolites and transformation products of VMPs could be found in manure. Mainly, the samples were analyzed for sulfonamides, tetracyclines and fluorquinolones. In no case a non-target approach was used. Single active substances were found in some studies with more than 100 analyzed samples in more than 50 % of the analyzed manure samples. This is the case for sulfadimidine, chlortetracycline, oxytetracycline, and tetracycline. It can be concluded that for both transformation studies and monitoring studies a standardized guidance would be beneficial for their applicability in regulatory contexts and also enhance the scientific outcome of these studies.en
dc.format.extent1Onlineressource (51 Seiten)
dc.format.mediumonline resource
dc.identifier.doihttps://doi.org/10.60810/openumwelt-6585
dc.identifier.urihttps://openumwelt.de/handle/123456789/6301
dc.language.isoeng
dc.relation.ispartofseriesTexte
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/
dc.subjectTierarzneimittel
dc.subjectGülle
dc.subjectPrüfvorschrift
dc.subjecttransformation
dc.subjectVeterinärpharmaka
dc.subjectBiozide
dc.subjectGülle
dc.subjectPrüfrichtlinie
dc.subjectveterinary medicinal
dc.subjectproducts
dc.subjectbiocides
dc.subjectmanure
dc.subjecttest guideline
dc.subject.ubaThemeChemikalien
dc.titleHarmonization of environmental exposure assessment for veterinary pharmaceuticals and biocides
dc.typeForschungsbericht
dc.typeMonographie
dc.type.dcmitext
dc.type.mediumcomputer
dspace.entity.typePublication
local.bibliographicCitation.number79/2016
local.bibliographicCitation.publisherPlaceDessau-Roßlau
local.collectionTexte / Umweltbundesamt
local.contributor.authorId02066846
local.contributor.authorId(DE-588)115820833
local.contributor.authorId02173595
local.contributor.authorId00420021
local.contributor.otherId02143078
local.contributor.otherId02163073
local.identifier.catalogId02454342
local.identifier.cmsId47735
local.identifier.fundingIndicator371265420
local.identifier.standardizedFundingIndicator37126542
local.ingest.catalogBCnumber79/2016
local.ingest.cmsBCnumber79/2016
local.ingest.cmsCreatedOn2016-11-25T12:52:02
local.ingest.cmsModifiedOn2016-11-25T14:41:48
local.ingest.cmsStateChangedOn2016-11-25T14:41:47
local.ingest.cmsStateNewLive (veröffentlicht)
local.ingest.cmsStateOldzur Freigabe
local.ingest.cmsStateRevisionId85208
local.ingest.leader06087nam a2200000uu 4500
local.jointTitleHARMONIZATION OF ENVIRONMENTAL EXPOSURE ASSESSMENT FOR VETERINARY PHARMACEUTICALS AND BIOCIDES LITERATURE REVIEW OF STUDIES ON OCCURRENCE AND TRANSFORMATION OF VETERINARY PHARMACEUTICALS AND BIOCIDES IN MANURE
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local.sourceenriched with cms, Id: 47735 at 2024-06-18T15:54:35.195755
local.source.urihttp://www.umweltbundesamt.de/publikationen/harmonization-of-environmental-exposure-assessment-0
local.subtitleliterature review of studies on occurrence and transformation of veterinary pharmaceuticals and biocides in manure
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