Publikation:
New models to predict the acute and chronic toxicities of representative species of the main trophic levels of aquatic environments

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dc.contributor.authorToma, Cosimo
dc.contributor.authorArning, Jürgen
dc.contributor.authorCappelli, Claudia Ileana
dc.contributor.authorManganaro, Alberto
dc.date.accessioned2024-06-16T13:29:15Z
dc.date.available2024-06-16T13:29:15Z
dc.date.issued2021
dc.description.abstractTo assess the impact of chemicals on an aquatic environment, toxicological data for three trophic levels are needed to address the chronic and acute toxicities. The use of non-testing methods, such as predictive computational models, was proposed to avoid or reduce the need for animal models and speed up the process when there are many substances to be tested. We developed predictive models for Raphidocelis subcapitata, Daphnia magna, and fish for acute and chronic toxicities. The random forest machine learning approach gave the best results. The models gave good statistical quality for all endpoints. These models are freely available for use as individual models in the VEGA platform and for prioritization in JANUS software. © 2021 by the authorsen
dc.format.extent1 Onlineresource (12 pages)
dc.format.mediumonline resource
dc.identifier.doihttps://doi.org/10.60810/openumwelt-1104
dc.identifier.urihttps://openumwelt.de/handle/123456789/3056
dc.language.isoeng
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/
dc.subjectFisch
dc.titleNew models to predict the acute and chronic toxicities of representative species of the main trophic levels of aquatic environments
dc.typeWissenschaftlicher Artikel
dc.type.dcmitext
dc.type.mediumcomputer
dspace.entity.typePublication
local.bibliographicCitation.journalTitleMolecules
local.bibliographicCitation.originalDOI10.3390/molecules26226983
local.bibliographicCitation.volume26 (2021), Heft 22
local.collectionAufsätze
local.contributor.authorId02184818
local.contributor.authorId02171899
local.contributor.authorId02172414
local.identifier.catalogId02487849
local.ingest.leader04203naa a2200000uu 4500
local.jointTitleNEW MODELS TO PREDICT THE ACUTE AND CHRONIC TOXICITIES OF REPRESENTATIVE SPECIES OF THE MAIN TROPHIC LEVELS OF AQUATIC ENVIRONMENTS
local.reviewtrue
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relation.isAuthorOfPublication.latestForDiscoverybb1c163d-200c-4bce-b0c9-31a04141c392
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