Person: Plaß, Dietrich
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Plaß
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Dietrich
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Publication Burden of infectious disease studies in Europe and the United Kingdom: a review of methodological design choices(2023) Charalampous, Periklis; Haagsma, Juanita A.; Jakobsen, Lea S.; Plaß, DietrichThis systematic literature review aimed to provide an overview of the characteristics and methods used in studies applying the disability-adjusted life years (DALY) concept for infectious diseases within European Union (EU)/European Economic Area (EEA)/European Free Trade Association (EFTA) countries and the United Kingdom. Electronic databases and grey literature were searched for articles reporting the assessment of DALY and its components. We considered studies in which researchers performed DALY calculations using primary epidemiological data input sources. We screened 3053 studies of which 2948 were excluded and 105 studies met our inclusion criteria. Of these studies, 22 were multi-country and 83 were single-country studies, of which 46 were from the Netherlands. Food- and water-borne diseases were the most frequently studied infectious diseases. Between 2015 and 2022, the number of burden of infectious disease studies was 1.6 times higher compared to that published between 2000 and 2014. Almost all studies (97%) estimated DALYs based on the incidence- and pathogen-based approach and without social weighting functions; however, there was less methodological consensus with regards to the disability weights and life tables that were applied. The number of burden of infectious disease studies undertaken across Europe has increased over time. Development and use of guidelines will promote performing burden of infectious disease studies and facilitate comparability of the results. Quelle:© The Author(s)Publication Krankheitslast durch Feinstaub(2017) Plaß, Dietrich; Tobollik, Myriam; Wintermeyer, DirkPublication Daten und Fakten zu Braun- und Steinkohlen(Umweltbundesamt, 2021) Baumgarten, Corinna; Beckers, Rolf; Bretschneider, Wolfgang; Briem, Sebastian; Frauenstein, Jörg; Gibis, Claudia; Gniffke, Patrick; Herbstritt, Caren; Grimm, Sabine; Juhrich, Kristina; Kahrl, Andreas; Kosmol, Jan; Kuhs, Gunter; Langner, Marcel; Lewandrowski, Dmitri; Lünenbürger, Benjamin; Mohaupt, Volker; Pfeiffer, David; Plaß, Dietrich; Plickert, Sebastian; Rechenberg, Jörg; Reißmann, Daniel; Sandau, Fabian; Straff, Wolfgang; Timme, Stephan; Weiß, Jan; Wintermeyer, DirkUm die weitere Ausgestaltung des Kohleausstiegs besteht weiterhin ein hoher Diskussion- und Entscheidungsbedarf. Um diesen gesellschaftlichen Diskussionsprozess zu begleiten, setzt das Umweltbundesamt mit diesem aktualisierten Hintergrundpapier seine Veröffentlichungsreihe "Daten und Fakten zu Braun- und Steinkohlen" fort. Die Publikation beleuchtet die aktuelle und perspektivische Rolle der Kohlen als Energieträger aus energiewirtschaftlicher, umweltpolitischer und ökonomischer Sicht (wie steigende Preise für CO2-Emissionszertifikate). Quelle: https://www.umweltbundesamt.dePublication Umweltbedingte Krankheitslasten in Deutschland(2018) Steckling, Nadine; Myck, Thomas; Mertes, Hanna; Plaß, Dietrich; Ziese, Thomas; Tobollik, Myriam; Wintermeyer, Dirk; Hornberg, ClaudiaPublication Ultrafeine Partikel in der Umgebungsluft - aktueller Wissensstand(2018) Becker, Kerstin; Birmili, Wolfram; Plaß, Dietrich; Süring, Katrin; Tobollik, MyriamUltrafeine Partikel (UFP) sind in den letzten Jahren zu einem häufig diskutierten Thema in der Luftreinhaltung geworden. Auch das Umweltbundesamt (UBA) erreichen aus Politik, Fachkreisen und der allgemeinen Öffentlichkeit zunehmend Fragen bezüglich der Bedeutung von UFP für Umwelt und Gesundheit. Der Artikel gibt einen Überblick zum aktuellen Stand des Wissens. Ausgehend von der Definition der UFP werden die Möglichkeiten ihrer Messung sowie die bislang nur eingeschränkt aussagekräftigen Erkenntnisse bezüglich ihrer gesundheitlichen Auswirkungen erläutert.Publication Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015(2016) Wang, Haidong; Naghavi, Mohsen; Allen, Christine; Barber, Ryan M.; Bhutta, Zulfiqar A.; Carter, Austin; Casey, Daniel C.; Charlson, Fiona J.; Chen, Alan Zian; Coates, Matthew M.; Coggeshall, Megan; Dandona, Lalit; Dicker, Daniel J.; Erskine, Holly E.; Ferrari, Alize J.; Fitzmaurice, Christina; Foreman, Kyle J.; Forouzanfar, Mohammad H.; Fraser, Maya S.; Fullman, Nancy; Gething, Peter W.; Goldberg, Ellen M.; Graetz, Nicholas; Haagsma, Juanita A.; Hay, Simon I.; Huynh, Chantal; Johnson, Catherine O.; Kassebaum, Nicholas J.; Kinfu, Yohannes; Kulikoff, Xie Rachel; Kutz, Michael; Kyu, Hmwe H.; Larson, Heidi J.; Leung, Janni; Liang, Xiaofeng; Lim, Stephen S.; Lind, Margaret; Lozano, Rafael; Marquez, Neal; Mensah, George A.; Mikesell, Joe; Mokdad, Ali H.; Mooney, Meghan D.; Nguyen, Grant; Nsoesie, Elaine; Pigott, David M.; Pinho, Christine; Roth, Gregory A.; Salomon, Joshua A.; Sandar, Logan; Silpakit, Naris; Sligar, Amber; Sorensen, Reed J. D.; Stanaway, Jeffrey; Steiner, Caitlyn; Teeple, Stephanie; Thomas, Bernadette A.; Troeger, Christopher; VanderZanden, Amelia; Vollset, Stein Emil; Plaß, Dietrich; Wanga, Valentine; Whiteford, Harvey A.; Wolock, Timothy; Zoeckler, Leo; Abate, Kalkidan Hassen; Abbafati, Cristiana; Abbas, Kaja M.; Abd-Allah, Foad; Abera, Semaw Ferede; Abreu, Daisy M. X.; Abu-Raddad, Laith J.; Abyu, Gebre Yitayih; Achoki, Tom; Adelekan, Ademola Lukman; Ademi, Zanfina; Adou, Arsène Kouablan; Adsuar, José C.; Afanvi, Kossivi AgbelenkoImproving survival and extending the longevity of life for all populations requires timely, robust evidence on local mortality levels and trends. The Global Burden of Disease 2015 Study (GBD 2015) provides a comprehensive assessment of all-cause and cause-specific mortality for 249 causes in 195 countries and territories from 1980 to 2015. These results informed an in-depth investigation of observed and expected mortality patterns based on sociodemographic measures. Quelle: www.sciencedirect.comPublication ICD-Codierung von Todesursachen(2019) Wengler, Annelene; Gruhl, Heike; Rommel, Alexander; Plaß, DietrichIm Projekt BURDEN 2020 - Die Krankheitslast in Deutschland und seinen Regionen - werden anhand der amtlichen Todesursachenstatistik die durch vorzeitige Sterblichkeit verlorenen Lebensjahre (Years of Life Lost, YLL) berechnet. Dafür müssen "ungültige ICD-Codes" identifiziert und umverteilt werden. "Ungültig" bedeutet, dass ein ICD-Code die Todesursache nur ungenügend wiedergibt, sodass er für die Berechnung der Krankheitslast nicht informativ ist. In diesem Artikel werden die ersten Schritte zur Berechnung der todesursachenspezifischen YLL dargestellt. Klassifizierungen ungültiger Codes werden verglichen. Es wird untersucht, wie viele Todesfälle mit ungültigen Codes in der Todesursachenstatistik in Deutschland absolut und relativ vorliegen und wie sich diese nach Alter, Geschlecht und Regionen verteilen. Auf Grundlage der Klassifikation der Weltgesundheitsorganisation (WHO) können für das Jahr 2015 in Deutschland bei den insgesamt 925.200 Todesfällen 15,6% ungültige Codes identifiziert werden. Nach der Klassifikation der Global Burden of Disease-Studie (GBD-Studie) des Institute for Health Metrics and Evaluation (IHME) liegt der Anteil bei 26,6%. Die ICD-bezogenen Verteilungsmuster unterscheiden sich bei WHO- und IHME-Klassifikation kaum. Große Unterschiede gibt es zwischen den Bundesländern: Der Anteil ungültiger Codes beträgt 16-35% (nach IHME-Klassifikation). Die Todesursachenstatistik in Deutschland enthält einen erheblichen Anteil an Todesfällen mit ungültigen Codes. Die Unterschiede zwischen den Bundesländern können nur teilweise mit der unterschiedlichen Verarbeitung der Daten erklärt werden. Zukünftig ist aufgrund der weiteren Verbreitung und Verbesserung der elektronischen Datenerfassung eine höhere Qualität der Todesursachenstatistik zu erwarten. Quelle: https://link.springer.com/Publication Estimating the morbidity related environmental burden of disease due to exposure to PM2.5, NO2 and O3 in outdoor ambient air(European Topic Centre on Human health and the environment, 2022) Kienzler, Sarah; Soares, Joana; Ortiz, Alberto González; Plaß, DietrichPublication Health Risk Assessment of Air Pollution: assessing the environmental burden of disease in Europe in 2021(ETC-HE, 2023) Soares, Joana; Kienzler, Sarah; Plaß, DietrichThis report presents the results of the environmental burden of disease (EBD) assessment related to air pollution in 2021 for the 27 Member States of the European Union and an additional 14 European countries (Albania, Andorra, Bosnia and Herzegovina, Iceland, Kosovo under UNSCR 1244/99, Liechtenstein, Monaco, Montenegro, North Macedonia, Norway, San Marino, Serbia, Switzerland, and Türkiye). The estimations differentiate the EBD by three individual pollutants, fine particulate matter (PM2.5), nitrogen dioxide (NO2), and ozone (O3), considering all-cause mortality as well as cause-specific mortality and morbidity. For the analyses, various burden of disease indicators were used, such as attributable deaths (AD), years of life lost (YLL), years lived with disability (YLD), disability-adjusted life years (DALY) and attributable hospitalisation cases. In 2021, long-term exposure to concentration levels above the WHO Air Quality Guideline levels of PM2.5 and NO2, resulted in 293 000 and 69 000 AD from all natural causes, respectively. There were 27 000 AD related to short-term exposure to O3. For EU27, the number of AD is 253 000, 52 000 and 22 000, respectively. When considering both the number of deaths and the age at which it occurs, the YLL (YLL per 100 000 inhabitants) is 2 936 000 (618) for long-term exposure to PM2.5 and 740 000 (132) to NO2, and 299 000 (54) due to short-term exposure to O3. For EU27, YLL (YLL per 100 000 inhabitants) are 2 584 000 (584), 532 000 (120), 234 000 (53), respectively. When comparing long-term exposure, both all-cause and cause-specific analyses point to PM2.5 as the pollutant with the highest burden. The cause-specific analyses resulted in 2 528 363 DALY in all countries or 2 310 387 DALY in the EU27. The burden attributable to NO2 was considerably lower, with 634 721 DALY and 403 788 DALY in all countries and in the EU27, respectively. Looking at the single disease entities, ischemic heart disease contributed the most to the overall burden of PM2.5, with 759 303 DALY in all countries and 704 525 DALY in the EU27. The lowest burden was related to Asthma (children), with 25 932 and 23 969 DALY in all countries and the EU27, respectively. For NO2, the highest disease burden was associated with diabetes mellitus (314 574 DALY; EU27: 197 031 DALY) and the lowest with asthma (adults) (all countries: 115 425 DALY; EU27: 62 460 DALY). No corresponding indicators were calculated for O3, yet short-term exposure to O3 was associated with 15 986 attributable hospital admissions in the selected European countries. When comparing the results, it is important to note that different age groups (i.e. children, adults, and elderly) were considered in the estimates, according to the relevant concentration-response functions. © European Topic Centre on Human Health and the Environment, 2023Publication The increasing significance of disease severity in a burden of disease framework(2021) Wyper, Grant M.A.; Assunção, Ricardo; Fletscher, Eilidh; Plaß, DietrichRecent estimates have reiterated that non-fatal causes of disease, such as low back pain, headaches and depressive disorders, are amongst the leading causes of disability-adjusted life years (DALYs). For these causes, the contribution of years lived with disability (YLD) - put simply, ill-health - is what drives DALYs, not mortality. Being able to monitor trends in YLD closely is particularly relevant for countries that sit high on the socio-demographic spectrum of development, as it contributes more than half of all DALYs. There is a paucity of data on how the population-level occurrence of disease is distributed according to severity, and as such, the majority of global and national efforts in monitoring YLD lack the ability to differentiate changes in severity across time and location. This raises uncertainties in interpreting these findings without triangulation with other relevant data sources. Our commentary aims to bring this issue to the forefront for users of burden of disease estimates, as its impact is often easily overlooked as part of the fundamental process of generating DALY estimates. Moreover, the wider health harms of the COVID-19 pandemic have underlined the likelihood of latent and delayed demand in accessing vital health and care services that will ultimately lead to exacerbated disease severity and health outcomes. This places increased importance on attempts to be able to differentiate by both the occurrence and severity of disease. © Author(s) 2021