Organisationseinheit: Deutschland. Umweltbundesamt. Fachgebiet IV.2.2 - Arzneimittel
Lade...
Ursprungsdatum
Stadt
Dessau-Roßlau
Land
ID
ROR Identifier
Publikationen
Arzneimittelindex Umwelt
(Umweltbundesamt, 2026) Vidaurre, Rodrigo; Heni, Yannick; Woitaske-Proske, Clemens; Peifer, Christian; Gassner, Ulrich
Arzneimittelrückstände in der Umwelt verschmutzen unsere Wasserressourcen und können erhebliche ökotoxikologische Probleme verursachen. Um die Wasserqualität zu erhalten, sind Maßnahmen in allen Phasen des Lebenszyklus eines Arzneimittels dringend notwendig – also auch bei der Anwendung. Eine Handlungsoption ist die Einführung des Arzneimittelindex Umwelt. Mit diesem Umweltinformations- und Klassifikationssystem können ökotoxikologische Informationen und Klassifizierungen in die pharmazeutische und medizinische Entscheidungsfindung im Rahmen der Verschreibung und Abgabe von Arzneimitteln einfließen. Das Konzept für dieses öffentlich zugängliche System sowie die Prüfung der Machbarkeit liegen jetzt vor.
Zu Risiken und Nebenwirkungen fragen Sie ... das Umweltbundesamt!
(Umweltbundesamt, 2026) Kemper, Melanie; Vidaurre, Rodrigo; Woitaske-Proske, Clemens
Arzneimittelrückstände in der Umwelt sind ein wachsendes Problem. Um einen umweltbewussten Umgang mit Humanarzneimitteln zu fördern, wurden frei verfügbare und editierbare Lehrmaterialien für die universitäre Lehre sowie für Fort- und Weiterbildungen entwickelt. Darüber hinaus wurden neue, freie und teils mehrsprachige Informationsmaterialien zur umweltbewussten Anwendung und Entsorgung von Medikamenten erstellt und verbreitet. Alle Materialien können über das UBA-Portal „Arzneimittel und Umwelt“ kostenfrei bestellt oder heruntergeladen werden: https://www.uba.de/ham.
EthoCRED: a framework to guide reporting and evaluation of the relevance and reliability of behavioural ecotoxicity studies
(2024) Bertram, Michael G.; Ågerstrand, Marlene; Thoré, Eli S.J.; Allen, Joel; Balshine, Sigal; Brand, Jack A.; Brooks, Bryan W.; Dang, ZhiChao; Duquesne, Sabine; Ford, Alex; Jacob, Stefanie; Maack, Gerd; Mohr, Silvia; Sahm, René
Behavioural analysis has been attracting significant attention as a broad indicator of sub-lethal toxicity and has secured a place as an important subdiscipline in ecotoxicology. Among the most notable characteristics of behavioural research, compared to other established approaches in sub-lethal ecotoxicology (e.g. reproductive and developmental bioassays), are the wide range of study designs being used and the diversity of endpoints considered. At the same time, environmental hazard and risk assessment, which underpins regulatory decisions to protect the environment from potentially harmful chemicals, often recommends that ecotoxicological data be produced following accepted and validated test guidelines. These guidelines typically do not address behavioural changes, meaning that these, often sensitive, effects are not represented in hazard and risk assessments. Here, we propose a new tool, the EthoCRED evaluation method, for assessing the relevance and reliability of behavioural ecotoxicity data, which considers the unique requirements and challenges encountered in this field. This method and accompanying reporting recommendations are designed to serve as an extension of the “Criteria for Reporting and Evaluating Ecotoxicity Data (CRED)” project. As such, EthoCRED can both accommodate the wide array of experimental design approaches seen in behavioural ecotoxicology, and could be readily implemented into regulatory frameworks as deemed appropriate by policy makers of different jurisdictions to allow better integration of knowledge gained from behavioural testing into environmental protection. Furthermore, through our reporting recommendations, we aim to improve the reporting of behavioural studies in the peer-reviewed literature, and thereby increase their usefulness to inform chemical regulation.
Environmental Pharmaceutical Index - a practical information, classification and dissemination system for medication in Germany
(2026) Woitaske-Proske, Clemens; Hein, Arne; Vidaurre, Rodrigo; Heni, Yannick; Peifer, Christian; Gassner, Ulrich M.; Maack, Gerd
Residues of pharmaceuticals in the environment can cause significant ecotoxicological issues but they also pose an imminent risk for human health e.g. by pollution of water resources used for food and drinking water production. Many active substances of pharmaceuticals for human use and their metabolites have been identified in the environment worldwide. To maintain water quality a variety of approaches during a pharmaceutical lifecycle are urgently needed, spanning actions from development, production over dispensing to end-of-pipe advanced wastewater treatments. In this paper, we report about a recently developed eco-directed pharmaceutical prescribing concept for Germany capable to trigger a significant beginning-of-the-pipe effect. The proposed system aims to balance therapeutical needs and environmental impacts by including ecotoxicological information and classification into pharmaceutical and medical decision making within the praxis of prescribing and dispensing medicines. We reviewed relevant existing eco-directed classification systems from Sweden, Finland, and Scotland. Based on these three different systems, we propose a practical environmental information, classification and dissemination system tailored to the German healthcare system, which combines positions from stakeholders including those responsible for regulation and health related data. Our results can be highly relevant to approaches aiming to establish similar systems in further countries. We identified the database ChemInfo hosted by the German Environment Agency as the central information system, for collecting environmental information from market authorisation processes. Our novel traffic light classification system is based on the hazard and risk outcomes of the environmental risk assessment and presents for the first time a European wide applicable environmental classification, capable of ranking pharmaceuticals within an indication group and identifying substances of concern to support decision making.
The classification system will label all pharmaceuticals, recently added to the EU list of priority substances within the Water Framework Directive, in red. Finally, we identified eight dissemination systems through which this information and classification can be included into decision making. © 2026 The Authors.
Beschreibung
Ergebnisse