Listen
10 Ergebnisse
Filter
Einstellungen
Suchergebnisse
Veröffentlichung Kopflausmittel mit Tilgungswirkung für den Infektionsschutz(2017) Habedank, BirgitVeröffentlichung Cold atmospheric pressure plasma comb - a physical approach for pediculosis treatment(2018) Bosch, Lars ten; Habedank, Birgit; Siebert, DominikPediculosis, that is the infestation of humans with Pediculus humanus capitis (head lice), poses a worldwide problem that is as old as mankind itself. Over the centuries, man has developed a variety of remedies, all of which have ultimately culminated in the use of chemical agents. Some of these remedies are known to produce successful results. A large portion of the effective remedies used to kill lice and their eggs contain insecticides, but there is an increasing number of reports of head lice populations revealing an increased resistance. This study presents an alternative treatment approach, the efficacy of which is based on physical effects. Cold atmospheric pressure plasmas have successfully shown their formidably wide application range within the field of plasma medicine. This study presents a plasma device in its current stage of development that is engineered as a consumer product to enable an alternative physical and insecticide-free option for the treatment of pediculosis. An efficacy study concerning different developmental stages of P. humanus humanus is presented. P. humanus humanus was chosen as a substitute test organism for P. humanus capitis due to possible laboratory rearing and high anatomic similarity. The study shows how a single stroke of the plasma device over a hair strand (approximately 22 cm in length with a weight of 1.5 g) led to mortality rates of 68.3% (50.0; 79.7) (95% CI) in the juvenile test group, a mortality rate of approx. 67.7% (54.9; 78.8) (95% CI) in the female test group, and approx. 46.7% (28.3; 65.7) (95% CI) in the male test group. When single eggs were introduced directly into the plasma for approx. 1 s, younger eggs (0-2 d) showed a higher mortality of 66.7% (42.7; 82.7) than the older (4-6 d) eggs, with 16.7% (5.6; 34.7) (CI). Furthermore, the results of a risk assessment of the device are described. The article concludes with necessary handling instructions as well as further developmental steps, derived from the results of the efficacy and the risk assessment study. Quelle: https://www.mdpi.comVeröffentlichung Research paper on abiotic factors and their influence on Ixodes ricinus activity-observations over a two-year period at several tick collection sites in Germany(2020) Gethmann, Jörn; Hoffmann, Bernd; Habedank, Birgit; Kasbohm, ElisaTick-borne diseases are a public health issue. To predict vector tick abundance and activity, it is necessary to understand the driving factors for these variables. In this study, the activity of Ixodes ricinus was investigated in forest and meadow habitats in Germany with a focus on abiotic factors. Ixodes ricinus adults, nymphs and larvae were caught by flagging over a period of 2 years. Microclimatic and weather conditions were recorded at the collection sites. Statistical models were applied to describe correlations between abiotic factors and tick activity in univariable and multivariable analyses. Tick activity was observed in a broad range of air temperature between 3 and 28 ˚C, and air humidity varied between 35 and 95%. In general, tick activity of nymphs and larvae was higher in forest habitats than that in meadows. With the exception of a single specimen of Dermacentor reticulatus, all ticks were Ixodes ricinus, most of them nymphs (63.2% in 2009 and 75.2% in 2010). For the latter, a negative binomial mixed-effects model fitted best to the observed parameters. The modelling results showed an activity optimum between 20 and 23 ˚C for air temperature and between 13 and 15 ˚C for ground temperature. In univariable analyses, the collection site, month, season, ground and air temperature were significant factors for the number of ticks caught and for all life stages. In the multivariable analysis, temperature, season and habitat turned out to be key drivers. Ixodes ricinus positive for RNA of tick-borne encephalitis virus was only found at a single sampling site. The results of this study can be used in risk assessments and to parameterise predictive models. © The Author(s) 2020Veröffentlichung International recommendations for an effective control of head louse infestations(2021) Mumcuoglu, Kosta Y.; Habedank, Birgit; Pollack, Richard J.; Reed, David L.Head louse infestations continue to be a concern of public health in most countries, including the most developed ones. The present recommendations are intended to inform and stress the role and impact of the different authorities, institutions, industry, and the public in the control of head lice in order to reduce the prevalence of this parasite. We encourage health authorities to pursue more effective methods to correctly identify such infestations, and evaluate existing and new pediculicides, medical devices, louse repellents, and louseâ€Ì and nitâ€Ìremoval remedies. Pediculicides and medical devices must have verifiable claims in the instructions for use and should be tested periodically to document current levels of resistance by lice to the active ingredients and to the formulated products. Where the prevalence of lice is claimed to be epidemic, children should be periodically evaluated objectively to document the actual level of prevalence. Continuing education for health providers and the general population promises to correct misinformation regarding the biology, prevention, and management of lice. Parents should regularly inspect their children for head lice and treat as necessary. Health authorities are encouraged to eliminate policies and practices that rely upon school exclusion as a means to reduce incidence and prevalence, e.g., the 'noâ€Ìnit' policy which lacks scientific justification, and are counterproductive to the health and welfare of children. © 2020 The Authors.Veröffentlichung Erratum: ten Bosch et al. Cold atmospheric pressure plasma comb - a physical approach for pediculosis treatment(2020) Bosch, Lars ten; Habedank, Birgit; Siebert, DominikVeröffentlichung Inhalation of publicly available indoor insecticide spray caused myocardial infarction type II: a case report(2021) Habedank, Dirk; Stubbe, Beate; Habedank, Birgit; Ewert, RalfWe report on a 70-year-old woman who tried to eliminate ants from her kitchen by applying a publicly available insecticide spray. Immediately afterwards, she felt dyspnoea, superseded by heavy chest pain. High-sensitivity troponin concentration increased from 33 to 149 ng/L (cut-off 50 ng/L). Significant coronary stenosis was excluded by coronary angiography, and the myocardial damage was classified as myocardial infarction type II. After exclusion of other potential mechanisms, we consider a cardiotoxic effect of the insecticide mixture of cypermethrin, tetramethrin, and piperonyl butoxide possible. We conclude that consumer information has to be improved. This concerns sustainable control measures adapted to the target insect species (in this case, the black garden ant Lasius niger), and differentiation between authorized and non-authorized but notified products. The instructions for use should give clear information on vulnerable groups and recommend personal protective equipment. Physicians and authorities should be alert to cardiac side-effects of insecticides. Source: https://onlinelibrary.wiley.comVeröffentlichung Light sheet fluorescence microscopy for the investigation of blood-sucking arthropods dyed via artificial membrane feeding(2022) Bosch, Lars ten; Candeo, Alessia; Bassi, Andrea; Valentini, Gianluca; Habedank, Birgit; Gerhard, ChristophPhysical methods to control pest arthropods are increasing in importance, but detailed knowledge of the effects of some of these methods on the target organisms is lacking. The aim of this study was to use light sheet fluorescence microscopy (LSFM) in anatomical studies of blood-sucking arthropods in vivo to assess the suitability of this method to investigate the morphological structures of arthropods and changes in these structures over time, using the human louse Pediculus humanus (Phthiraptera: Pediculidae) as sample organism. Plasma treatment was used as an example of a procedure employed to control arthropods. The lice were prepared using an artificial membrane feeding method involving the ingestion of human blood alone and human blood with an added fluorescent dye in vitro. It was shown that such staining leads to a notable enhancement of the imaging contrast with respect to unstained whole lice and internal organs that can normally not be viewed by transmission microscopy but which become visible by this approach. Some lice were subjected to plasma treatment to inflict damage to the organisms, which were then compared to untreated lice. Using LSFM, a change in morphology due to plasma treatment was observed. These results demonstrate that fluorescence staining coupled with LSFM represents a powerful and straightforward method enabling the investigation of the morphology - including anatomy - of blood-sucking lice and other arthropods. © The Author(s) 2022.Veröffentlichung Auswirkungen von Klimaveränderungen auf Vektor- und Nagetier-assoziierte Infektionskrankheiten(2023) Beermann, Sandra; Dobler, Gerhard; Faber, Mirko; Habedank, Birgit; Kuhn, Carola; Schmolz, ErikVeröffentlichung Impact of climate change on vector- and rodent-borne infectious diseases(2023) Beermann, Sandra; Dobler, Gerhard; Faber, Mirko; Habedank, Birgit; Kuhn, Carola; Schmolz, ErikBackground: Endemic and imported vector- and rodent-borne infectious agents can be linked to high morbidity and mortality. Therefore, vector- and rodent-borne human diseases and the effects of climate change are important public health issues. Methods: For this review, the relevant literature was identified and evaluated according to the thematic aspects and supplemented with an analysis of surveillance data for Germany. Results: Factors such as increasing temperatures, changing precipitation patterns, and human behaviour may influence the epidemiology of vector- and rodent-borne infectious diseases in Germany. Conclusions: The effects of climatic changes on the spread of vector- and rodent-borne infectious diseases need to be further studied in detail and considered in the context of climate adaptation measures. Quelle: Journal of health monitoring / Robert Koch-Institut. - 8 (2023), Heft S3, page 33Veröffentlichung Auswirkungen von Klimaveränderungen auf Vektor- und Nagetier-assoziierte Infektionskrankheiten(2023) Beermann, Sandra; Dobler, Gerhard; Faber, Mirko; Habedank, Birgit; Kuhn, Carola; Schmolz, ErikHintergrund: Endemische wie auch importierte Vektor- und Nagetier-übertragene Infektionserreger können mit hoher Morbidität und Mortalität assoziiert sein. Daher sind Vektor- und Nagetier-assoziierte Erkrankungen des Menschen und deren mögliche Beeinflussung durch klimatische Veränderungen ein wichtiges Thema für die öffentliche Gesundheit. Methode: Für diese Übersichtsarbeit wurde die Literatur entsprechend der thematisierten Aspekte identifiziert, ausgewertet und durch Meldedaten für Deutschland ergänzt. Ergebnisse: Faktoren wie höhere Temperaturen, veränderte Niederschlagsmuster und das Verhalten der Menschen können die Epidemiologie von Vektor- und Nagetier-assoziierten Infektionskrankheiten in Deutschland beeinflussen. Schlussfolgerungen: Die Auswirkungen von klimatischen Veränderungen auf die Ausbreitung der Vektor- und Nagetierassoziierten Infektionskrankheiten müssen im Detail weiter untersucht und bei Klimaanpassungsmaßnahmen berücksichtigt werden. Quelle: Journal of health monitoring / Robert Koch-Institut - 8 (2023), Heft S3, Seite 36