Publikation:
Pharmaceuticals in the environment

dc.contributor.authorKüster, Anette
dc.contributor.authorAdler, Nicole
dc.date.accessioned2024-06-16T16:21:19Z
dc.date.available2024-06-16T16:21:19Z
dc.date.issued2014
dc.description.abstractDuring the past two decades scientists, regulatory agencies and the European Commission have acknowledged pharmaceuticals to be an emerging environmental problem. In parallel, a regulatory framework for environmental risk assessment (ERA) of pharmaceutical products has been developed. Since the regulatory guidelines came into force the German Federal Agency (UBA) has been evaluating ERAs for human and veterinary pharmaceutical products before they are marketed. The results show that approximately 10% of pharmaceutical products are of note regarding their potential environmental risk. For human medicinal products, hormones, antibiotics, analgesics, antidepressants and antineoplastics indicated an environmental risk. For veterinary products, hormones, antibiotics and parasiticides were most often discussed as being environmentally relevant. These results are in good correlation with the results within the open scientific literature of prioritization approaches for pharmaceuticals in the environment. UBA results revealed that prospective approaches, such as ERA of pharmaceuticals, play an important role in minimizing problems caused by pharmaceuticals in the environment. However, the regulatory ERA framework could be improved by (i) inclusion of the environment in the risk-benefit analysis for human pharmaceuticals, (ii) improvement of risk management options, (iii) generation of data on existing pharmaceuticals, and (iv) improving the availability of ERA data. In addition, more general and integrative steps of regulation, legislation and research have been developed and are presented in this article. In order to minimize the quantity of pharmaceuticals in the environment these should aim to (i) improve the existing legislation for pharmaceuticals, (ii) prioritize pharmaceuticals in the environment and (iii) improve the availability and collection of pharmaceutical data.<BR>Quelle: http://www.researchgate.net/en
dc.identifier.doihttps://doi.org/10.60810/openumwelt-2043
dc.identifier.urihttps://openumwelt.de/handle/123456789/8530
dc.language.isoeng
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/
dc.subjectRegulierung
dc.subjectUmweltrisikobewertung
dc.subjectMonitoring
dc.titlePharmaceuticals in the environment
dc.typeWissenschaftlicher Artikel
dspace.entity.typePublication
local.bibliographicCitation.journalTitlePhilosophical Transactions of the Royal Society of London
local.bibliographicCitation.originalDOI10.1098/rstb.2013.0587
local.bibliographicCitation.volume369 (2014), H. 1656, [online article]
local.collectionAufsätze
local.contributor.authorId02141002
local.identifier.catalogId02413665
local.ingest.leader05065naa a2200000uu 4500
local.jointTitlePHARMACEUTICALS IN THE ENVIRONMENT SCIENTIFIC EVIDENCE OF RISKS AND ITS REGULATION
local.sourcecatalog
local.source.urihttp://webde/gruppen/bibliothek/Einzelaufsaetze/Einzelaufsaetze-EA/EA003871.pdf
local.staffPublicationtrue
local.subtitlescientific evidence of risks and its regulation
relation.isAuthorOfPublicationac5522f1-691f-4220-94df-23b2510c6302
relation.isAuthorOfPublication.latestForDiscoveryac5522f1-691f-4220-94df-23b2510c6302
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