Publikation:
New specific and sensitive biomonitoring methods for chemicals of emerging health relevance

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dc.contributor.authorLeng, Gabriele
dc.contributor.authorFiddicke, Ulrike
dc.contributor.authorGries, Wolfgang
dc.contributor.authorKolossa-Gehring, Marike
dc.date.accessioned2024-06-16T15:46:18Z
dc.date.available2024-06-16T15:46:18Z
dc.date.issued2017
dc.description.abstractIn this publication the challenges to cope for the aim to obtain innovative biomonitoring methods in our laboratory are visualized for di(2-propylheptyl)phthalate, 2-mercaptobenzothiazole, 3,5-di-tert-butyl-4-hydroxytoluene, 4-nonylphenol, 4-tert-octylphenol, 3-(4-methylbenzylidene)camphor, 4,4'-methylene diphenyl diisocyanate, and Hexabromocyclododecane. For these substances new specific markers were explored based on animal or human kinetic data with urine being the preferred matrix compared to blood. The determination of these markers was complex in all cases, because the sample preparation as well as the detection by high performance liquid chromatography, capillary gas chromatography coupled to tandem mass spectrometers or high resolution mass spectrometry should enable the lowest possible detection limit by use of minimal biological sample volumes. To get a first hint of a possible background level, the analytical methods were applied to urine samples of about 40 persons for each chemical. For Di(2-propylheptyl)phthalate and 2-Mercaptobenzothiazole first results are presented from population biomonitoring. Quelle: http://www.sciencedirect.comen
dc.format.extent1 Onlineressource
dc.format.mediumonline resource
dc.identifier.doihttps://doi.org/10.60810/openumwelt-1865
dc.identifier.urihttps://openumwelt.de/handle/123456789/7249
dc.language.isoger
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/
dc.subjectBiomonitoring
dc.titleNew specific and sensitive biomonitoring methods for chemicals of emerging health relevance
dc.typeWissenschaftlicher Artikel
dc.type.dcmitext
dc.type.mediumcomputer
dspace.entity.typePublication
local.bibliographicCitation.journalTitleInternational Journal of Hygiene and Environmental Health
local.bibliographicCitation.originalDOI10.1016/j.ijheh.2016.09.014
local.bibliographicCitation.volume220 (2017), Heft 2
local.collectionAufsätze
local.contributor.authorId00341949
local.contributor.authorId02165863
local.identifier.catalogId02440595
local.ingest.leader05175naa a2200000uu 4500
local.jointTitleNEW SPECIFIC AND SENSITIVE BIOMONITORING METHODS FOR CHEMICALS OF EMERGING HEALTH RELEVANCE REVIEW
local.sourcecatalog
local.source.urihttp://www.sciencedirect.com/science/article/pii/S1438463916301067
local.staffPublicationtrue
local.subtitleReview
relation.isAuthorOfPublication2479b223-fd89-45bd-84c0-70945fa90155
relation.isAuthorOfPublication0c3b6c3e-eff4-42d8-94e9-07a4fee4049c
relation.isAuthorOfPublication.latestForDiscovery2479b223-fd89-45bd-84c0-70945fa90155
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