Publikation:
Silylation: a reproducible method for characterization of non-extractable residues (NER) of organic chemicals in the assessment of persistence

Kurzanzeige
dc.contributor.authorHennecke, Dieter
dc.contributor.authorKruse, Mike
dc.contributor.authorClaßen, Daniela
dc.contributor.authorBräutigam, Joana
dc.date.accessioned2024-06-16T12:38:57Z
dc.date.available2024-06-16T12:38:57Z
dc.date.issued2023
dc.description.abstractMost, if not all, chemicals, biocides, pharmaceuticals and pesticides are known to produce non-extractable residues (NER) in solid environmental media like soil and sediment during degradation testing to various extents. Since it has been found that parent substances and relevant metabolites can be contained and potentially released from NER there is currently much debate on how to include NER in the environmental persistence assessment. Using radioactive or stable isotope labelled test substances, three types of NER can be experimentally discriminated: entrapped, sorbed or heavily sorbed (type I) having the potential to be released from the matrix. Type II NER, i.e. residues covalently bound to organic matter in soils or sediments, are being considered to have very low remobilisation potential. Type III NER (bioNER) are formed after degradation of the xenobiotic chemical and incorporation into natural biomolecules (anabolism) like amino acids and other biomass compounds, and are, thus, of no environmental concern. Silylation has been suggested as a methodology to differentiate types I and II NER but concern has been addressed that this procedure is not suitable for routine analysis, e.g. in the context of studies for authorisation and registration of chemicals. Here, we describe a readily applicable and reproducible experimental procedure to apply this method for the analysis of NER derived from bromoxynil, sulfadiazine and isoproturon, respectively. This method is able to distinguish between heavily sorbed and covalently bound residues of chemicals, biocides, pharmaceuticals and pesticides in soils and to subsequently identify residues of the parent substance entrapped in type I NER. © 2023 The Author(s). Published by the Royal Society of Chemistryen
dc.format.extent1 Online-Resource (9 pages)
dc.format.mediumonline resource
dc.identifier.doihttps://doi.org/10.60810/openumwelt-1547
dc.identifier.urihttps://openumwelt.de/handle/123456789/1538
dc.language.isoeng
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/
dc.titleSilylation: a reproducible method for characterization of non-extractable residues (NER) of organic chemicals in the assessment of persistence
dc.typeWissenschaftlicher Artikel
dc.type.dcmitext
dc.type.mediumcomputer
dspace.entity.typePublication
local.bibliographicCitation.journalTitleEnvironmental Science: Advances
local.bibliographicCitation.originalDOI10.1039/d2va00314g
local.bibliographicCitation.volume2 (2023)
local.collectionAufsätze
local.contributor.authorId02065749
local.contributor.authorId02193105
local.contributor.authorId02193106
local.identifier.catalogId02501660
local.ingest.leader05329naa a2200000uu 4500
local.jointTitleSILYLATION A REPRODUCIBLE METHOD FOR CHARACTERIZATION OF NONEXTRACTABLE RESIDUES NER OF ORGANIC CHEMICALS IN THE ASSESSMENT OF PERSISTENCE
local.reviewtrue
local.sourcecatalog
local.source.urihttp://creativecommons.org/licenses/by/4.0/deed.de
local.staffPublicationtrue
relation.isAuthorOfPublication37eefbcf-d144-4f1f-9d37-bc3900d4f328
relation.isAuthorOfPublication.latestForDiscovery37eefbcf-d144-4f1f-9d37-bc3900d4f328
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