Publikation:
Levels and predictors of urinary nickel concentrations of children in Germany: Results from the German Environmental Survey on children (GerES IV)

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dc.date.accessioned2024-06-16T16:37:52Z
dc.date.available2024-06-16T16:37:52Z
dc.date.issued2013
dc.description.abstractHuman biomonitoring of nickel has gained interest in environmental medicine due to its wide distribution in the environment and its allergenic potential. There are indications that the prevalence of nickel sensitization in children is increased by nickel exposure and that oral uptake of nickel can exacerbate nickel dermatitis in nickel-sensitive individuals. Urinary nickel measurement is a good indicator of exposure. However, data on nickel levels in urine of children are rare. For the first time, the German Environmental Survey on children (GerES IV) 2003-2006 provided representative data to describe the internal nickel exposure of children aged 3-14 years in Germany. Nickel was measured after enrichment in the organic phase of urine by graphite furnace atomic absorption spectrometry with Zeeman background correction. Nickel levels (n = 1576) ranged from <0.5 to 15 ĆÊg/l. Geometric mean was 1.26 ĆÊg/l. Multivariate regression analysis showed that gender, age, socio-economic status, being overweighted, consumption of hazelnut spread, nuts, cereals, chocolate and urinary creatinine were significant predictors for urinary nickel excretion of children who do not smoke. 20.2% of the variance could be explained by these variables. With a contribution of 13.8% the urinary creatinine concentration was the most important predictor. No influence of nickel intake via drinking water and second hand smoke exposure was observed.Copyright ©2012 Published by Elsevier GmbH.<BR>en
dc.identifier.doihttps://doi.org/10.60810/openumwelt-1133
dc.identifier.urihttps://openumwelt.de/handle/123456789/9366
dc.language.isoeng
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/
dc.subjectHuman-Biomonitoring
dc.subjectNickel
dc.subjectHarn
dc.subjectUmwelt-Survey [Bevölkerungsexposition]
dc.subjectUmweltmedizin
dc.subjectBundesrepublik Deutschland
dc.titleLevels and predictors of urinary nickel concentrations of children in Germany: Results from the German Environmental Survey on children (GerES IV)
dc.typeWissenschaftlicher Artikel
dspace.entity.typePublication
local.bibliographicCitation.journalTitleInternational Journal of Hygiene and Environmental Health
local.bibliographicCitation.originalDOI10.1016/j.ijheh.2012.03.008
local.bibliographicCitation.volume216 (2013), H. 2, Seite 163-169
local.collectionAufsätze
local.identifier.catalogId02372388
local.ingest.leader06488naa a2200000uu 4500
local.jointTitleLEVELS AND PREDICTORS OF URINARY NICKEL CONCENTRATIONS OF CHILDREN IN GERMANY RESULTS FROM THE GERMAN ENVIRONMENTAL SURVEY ON CHILDREN GERES IV
local.sourcecatalog
local.source.urihttp://www.sciencedirect.com/science/article/pii/S1438463912000478
local.staffPublicationtrue
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