Publikation:
Human biomonitoring pilot study DEMOCOPHES in Germany: Contribution to a harmonized European approach

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dc.contributor.authorFiddicke, Ulrike
dc.contributor.authorIßleb, Sissy
dc.contributor.authorKolossa-Gehring, Marike
dc.contributor.authorSchwedler, Gerda
dc.contributor.authorSeiwert, Margarete
dc.date.accessioned2024-06-16T15:34:50Z
dc.date.available2024-06-16T15:34:50Z
dc.date.issued2017
dc.description.abstractHuman biomonitoring (HBM) is an effective tool to assess human exposure to environmental pollutants, but comparable HBM data in Europe are lacking. In order to expedite harmonization of HBM studies on a European scale, the twin projects COPHES (Consortium to Perform Human Biomonitoring on a European Scale) and DEMOCOPHES (Demonstration of a study to Coordinate and Perform Human Biomonitoring on a European Scale) were formed, comprising 35 partners from 27 European countries. In COPHES a research scheme and guidelines were developed to exemplarily measure in a pilot study mercury in hair, cadmium, cotinine and several phthalate metabolites in urine of 6Ń11 year old children and their mothers in an urban and a rural region. Seventeen European countries simultaneously conducted this cross-sectional DEMOCOPHES feasibility study. The German study population was taken in the city of Bochum and in the Higher Sauerland District, comprising 120 mother-child pairs. In the present paper features of the study implementation are presented. German exposure concentrations of the pollutants are reported and compared with European average concentrations from DEMOCOPHES and with those measured in the representative German Environmental Survey (GerES IV). German DEMOCOPHES concentrations for mercury and cotinine were lower than the European average. However, 47% of the children were still exposed to environmental tobacco smoke (ETS) outside their home, which gives further potential for enhancing protection of children from ETS. Compared with samples from the other European countries German participating children had lower concentrations of the phthalate metabolites MEP and of the sum of 3 DEHP-metabolites (MEHP, 5OH-MEHP and 5oxo-MEHP), about the same concentrations of the phthalate metabolites MBzP and MiBP and higher concentrations of the phthalate metabolite MnBP. 2.5% of the German children had concentrations of the sum of 4 DEHP-metabolites and 4.2% had concentrations of MnBP that exceeded health based guidance values, indicating reasons for concern. Continuous HBM is necessary to track changes of pollutant exposure over time. Therefore Germany will continue to cooperate on the harmonisation of European human biomonitoring to support the chemicals regulation with the best possible exposure data to protect Europe's people against environmental health risks. Quelle: http://www.sciencedirect.comen
dc.format.extent1 Onlineressource (11 Seiten)
dc.format.mediumonline resource
dc.identifier.doihttps://doi.org/10.60810/openumwelt-929
dc.identifier.urihttps://openumwelt.de/handle/123456789/6876
dc.language.isoger
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/
dc.titleHuman biomonitoring pilot study DEMOCOPHES in Germany: Contribution to a harmonized European approach
dc.typeWissenschaftlicher Artikel
dc.type.dcmitext
dc.type.mediumcomputer
dspace.entity.typePublication
local.bibliographicCitation.journalTitleInternational Journal of Hygiene and Environmental Health
local.bibliographicCitation.originalDOI10.1016/j.ijheh.2
local.bibliographicCitation.volume220 (2017), Heft 4
local.collectionAufsätze
local.contributor.authorId(DE-588)1158378610
local.identifier.catalogId02444693
local.ingest.leader06128naa a2200000uu 4500
local.jointTitleHUMAN BIOMONITORING PILOT STUDY DEMOCOPHES IN GERMANY CONTRIBUTION TO A HARMONIZED EUROPEAN APPROACH
local.sourcecatalog
local.source.urihttp://www.sciencedirect.com/science/article/pii/S1438463916304278
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