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Analysis of 18 mercapturic acids in urine samples from the German Environmental Specimen Bank - tackling the data gap in the human biomonitoring of VOCs in Europe

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dc.contributor.authorPluym, Nikola
dc.contributor.authorBurkhardt, Therese
dc.contributor.authorWeber, Till
dc.contributor.authorScherer, Gerhard
dc.contributor.authorScherer, Max
dc.contributor.authorKolossa-Gehring, Marike
dc.date.issued2026
dc.description.abstractComprehensive human biomonitoring (HBM) data with regard to the exposure to volatile organic compounds (VOCs) in Europe is lacking. This prompted us to quantify 18 mercapturic acids as urinary VOC metabolites in 360 samples from the Environmental Specimen Bank collected between 2000 and 2021 in Germany. Our study demonstrates the ubiquitous exposure to numerous VOCs of high toxicological relevance, albeit with a decreasing trend over time for most of the metabolites. This emphasizes the need for a broader HBM to better understand the risk of VOC exposure in Germany and more general in Europe. ©The Author(s) 2026
dc.identifier.doihttps://doi.org/10.60810/openumwelt-8704
dc.identifier.urihttps://openumwelt.de/handle/123456789/12154
dc.language.isoen
dc.relation.isOrgUnitOfDeutschland. Umweltbundesamt. Fachgebiet II.1.2 - Toxikologie, gesundheitsbezogene Umweltbeobachtung
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectVOC
dc.subjectHuman Biomonitoring (HBM)
dc.subjectTime trend
dc.subjectEnvironmental Specimen Bank
dc.subjectExposure assessment
dc.subjectMercapturic acid
dc.subject.ddc500 Naturwissenschaften und Mathematik::500 Naturwissenschaften
dc.subject.ubaThemeGesundheit
dc.titleAnalysis of 18 mercapturic acids in urine samples from the German Environmental Specimen Bank - tackling the data gap in the human biomonitoring of VOCs in Europe
dc.typeWissenschaftlicher Artikel
dspace.entity.typePublication
local.accessRights.dnbfree
local.bibliographicCitation.journalTitleJournal of exposure science and environmental epidemiology
local.bibliographicCitation.originalDOIhttp://doi.org/10.1038/s41370-026-00838-x
local.bibliographicCitation.pageEnd503
local.bibliographicCitation.pageStart490
local.bibliographicCitation.publisherPlaceBasingstoke
local.bibliographicCitation.volume36
local.reviewPeer-reviewed
local.versionTypehttp://purl.org/coar/version/c_970fb48d4fbd8a85
relation.isAuthorOfPublication800537d2-ed95-4cc9-973c-d54784b3cb09
relation.isAuthorOfPublication0c3b6c3e-eff4-42d8-94e9-07a4fee4049c
relation.isAuthorOfPublication.latestForDiscovery800537d2-ed95-4cc9-973c-d54784b3cb09
relation.isOrgUnitOfPublication23a04e6c-fb98-442b-b320-7092fccbfcd4
relation.isOrgUnitOfPublication.latestForDiscovery23a04e6c-fb98-442b-b320-7092fccbfcd4

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