Vorschaubild nicht verfügbar
Publikationstyp
Conference proceedings
Monographie
Monographie
Erscheinungsjahr
2014
DOI
The German Environmental Specimen Bank - Human exposure to emerging chemicals and their regulation
The German Environmental Specimen Bank - Human exposure to emerging chemicals and their regulation
Autor:innen
Herausgeber
Quelle
Annual Meeting of European, Middle Eastern & African Society for Biopreservation & Biobanking
Schlagwörter
Zitation
The German Environmental Specimen Bank - Human exposure to emerging chemicals and their regulation, 2014. [online]. Verfügbar unter: https://openumwelt.de/handle/123456789/8581
Zusammenfassung englisch
Europeans are still substantially exposed tochemicals. Toxicological and epidemiological studies
have revealed several associations between exposureand health effects for numerous substances. InGermany exposure to various chemicals is well documentedby the German Environmental Survey (GerES)and the Environmental Specimen Bank CESB). Many relevantsources of exposure and chemicals of concernhave changed over time: While in the past ambient airand drinking water were particularly important, today'smain sources are nutrition, indoor air, cosmetics, andconsumer products. After identification of substancesof toxicological relevance and to which the generalpopulation might considerably be exposed new humanbiomonitoring (HBM) methods for i. a. the sensitizingagent methylenediphenyldiisocyanate (MDI), the two
plasticisers Hexamoll® DI NCH®,Di-2-propylheptylphthalate CDPHP)- both substitutes for Di-2-ethylhexylphthalate (DEHP)- and parabenes have beendeveloped and-if appropriate- applied to ESB samples.While MDI and DPHP seem not to be related with ameasurable exposure of occupationally non-exposedpersons, DINCH levels increase constantly since marketingof this new substance.The relevance of thesefindings is to be assessed by derivation of toxicological
Human-Biomonitoring-Values as well as by HBMstudies in the population-representative GerES V. ln vestigationof chemicals relevant today by HBM helpsto prioritize futher toxicological investigations andprovides guidance for consumer decisions and policy.However, a continuous monitoring also of well knownsubstances is essential for assessing impacts of chemicals
on children. GerES and ESB are funded by theFederal Ministries for the Environment as well as Educationand Research.
Quelle: Programme Book : ESBB Annual Meeting, October 21-24, 2014 / ESBB. Leipzig, 2014, S. 32-33
have revealed several associations between exposureand health effects for numerous substances. InGermany exposure to various chemicals is well documentedby the German Environmental Survey (GerES)and the Environmental Specimen Bank CESB). Many relevantsources of exposure and chemicals of concernhave changed over time: While in the past ambient airand drinking water were particularly important, today'smain sources are nutrition, indoor air, cosmetics, andconsumer products. After identification of substancesof toxicological relevance and to which the generalpopulation might considerably be exposed new humanbiomonitoring (HBM) methods for i. a. the sensitizingagent methylenediphenyldiisocyanate (MDI), the two
plasticisers Hexamoll® DI NCH®,Di-2-propylheptylphthalate CDPHP)- both substitutes for Di-2-ethylhexylphthalate (DEHP)- and parabenes have beendeveloped and-if appropriate- applied to ESB samples.While MDI and DPHP seem not to be related with ameasurable exposure of occupationally non-exposedpersons, DINCH levels increase constantly since marketingof this new substance.The relevance of thesefindings is to be assessed by derivation of toxicological
Human-Biomonitoring-Values as well as by HBMstudies in the population-representative GerES V. ln vestigationof chemicals relevant today by HBM helpsto prioritize futher toxicological investigations andprovides guidance for consumer decisions and policy.However, a continuous monitoring also of well knownsubstances is essential for assessing impacts of chemicals
on children. GerES and ESB are funded by theFederal Ministries for the Environment as well as Educationand Research.
Quelle: Programme Book : ESBB Annual Meeting, October 21-24, 2014 / ESBB. Leipzig, 2014, S. 32-33