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Publikationstyp
Conference proceedings
Monographie
Monographie
Erscheinungsjahr
2013
DOI
Interpreting biomarker data from the COPHES-DEMOCOPHES twin projects: Using lifestyle and environmental data to understand biomarker differences among countries
Interpreting biomarker data from the COPHES-DEMOCOPHES twin projects: Using lifestyle and environmental data to understand biomarker differences among countries
Herausgeber
Quelle
The 9th International Symposium on Biological Monitoring in Occupational and Environmental Health
Schlagwörter
Zitation
DEN HOND, Elly, Eva GOVARTS, Gudrun KOPPEN, Hanny WILLEMS, Reinhard JOAS, Ludwine CASTELEYN, Anke JOAS, Pierre BIOT, Dominique AERTS, Jürgen ANGERER, Marika BERGLUND, Louis BLOEMEN, Argelia CASTAÑO, Ulrike FIDDICKE, Milena CERNA, Pierre CRETTAZ, Marta ESTEBAN, Karen EXLEY, Eleonora FABIANOVA, Marc FISCHER, Arno Christian GUTLEB, Adamos HADJIPANAYIS, Katarina HALZLOVA, Milena HORVAT, Marek JAKUBOWSKI, Andromachi KATSONOURI, Marike KOLOSSA-GEHRING, Lisbeth E. KNUDSEN, Holger KOCH, Andrea KRSKOVA, Andreas LEHMANN, Danuta LIGOCKA, Ioana-Rodica LUPSA, Darja MAZEJ, Maurice MULCAHY, Sónia NAMORADO, Jeanette NIELSEN, Gerda SCHWEDLER und Fátima M. REIS, 2013. Interpreting biomarker data from the COPHES-DEMOCOPHES twin projects: Using lifestyle and environmental data to understand biomarker differences among countries [online]. Verfügbar unter: https://openumwelt.de/handle/123456789/8619
Zusammenfassung englisch
In 2011 and 2012, the COPHES/DEMOCOPHES twin projects performed a first ever harmonized human biomonitoring survey in 17 European countries. In more than 1800 mother-child pairs, cadmium, cotinine and certain phthalate metabolites were measured in urine, and total mercury in hair samples. The presentation provides an overview of the analyses that studied whether it was feasible to interpret the observed differences in biomarker values among different countries, using external databases on environmental quality and lifestyle.
Despite the fact that harmonised biomonitoring data was available from 17 different European countries, the assessment was hampered by a lack of consistent data on lifestyle and environmental quality. This implied that most analyses could only be performed for about half to two thirds of the participating countries. Nonetheless, it was feasible to relate aggregated fish consumption data to mercury in hair, to relate the strength of anti-smoking legislation to urinary cotinine levels, and to find a borderline significant relationship between cadmium levels in air or food and urinary cadmium levels across DEMOCOPHES countries. However, the challenge to integrate environmental exposure and lifestyle data with biomarker data is to have data available on a similar geographical resolution and therefore remains a pitfall for human biomonitoring to achieve its true potential for evidence-based policy making.
With many thanks to the COPHES consortium funded by DG RTD under FP7 and DEMOCOPHES co-funded under Life+, as well as the Ministries of the DEMOCOPHES countries, for the support. www.eu-hbm.info
Despite the fact that harmonised biomonitoring data was available from 17 different European countries, the assessment was hampered by a lack of consistent data on lifestyle and environmental quality. This implied that most analyses could only be performed for about half to two thirds of the participating countries. Nonetheless, it was feasible to relate aggregated fish consumption data to mercury in hair, to relate the strength of anti-smoking legislation to urinary cotinine levels, and to find a borderline significant relationship between cadmium levels in air or food and urinary cadmium levels across DEMOCOPHES countries. However, the challenge to integrate environmental exposure and lifestyle data with biomarker data is to have data available on a similar geographical resolution and therefore remains a pitfall for human biomonitoring to achieve its true potential for evidence-based policy making.
With many thanks to the COPHES consortium funded by DG RTD under FP7 and DEMOCOPHES co-funded under Life+, as well as the Ministries of the DEMOCOPHES countries, for the support. www.eu-hbm.info
Roel Smolders, et al.: Interpreting biomarker data from the COPHES-DEMOCOPHES twin projects: Using lifestyle and environmental data to understand biomarker differences among countries. In: Abstracts / The 9thInternational Symposium on Biological Monitoring in Occupational and Environmental Health. 2013, Manchester, S. 33