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Publikationstyp
Wissenschaftlicher Artikel
Erscheinungsjahr
2023
Time Patterns in Internal Human Exposure Data to Bisphenols, Phthalates, DINCH, Organophosphate Flame Retardants, Cadmium and Polyaromatic Hydrocarbons in Europe
Time Patterns in Internal Human Exposure Data to Bisphenols, Phthalates, DINCH, Organophosphate Flame Retardants, Cadmium and Polyaromatic Hydrocarbons in Europe
Autor:innen
Martin, Laura Rodriguez
Gilles, Liese
Helte, Emilie
Herausgeber
Quelle
Toxics
11 (2023), Heft 819
11 (2023), Heft 819
Schlagwörter
Human-Biomonitoring, DINCH, Cadmium, Bisphenole
Zitation
MARTIN, Laura Rodriguez, Liese GILLES, Emilie HELTE, Marike KOLOSSA-GEHRING, Rosa LANGE, Kim Laura PACK, Phillipp SCHMIDT, Nina VOGEL und Till WEBER, 2023. Time Patterns in Internal Human Exposure Data to Bisphenols, Phthalates, DINCH, Organophosphate Flame Retardants, Cadmium and Polyaromatic Hydrocarbons in Europe. Toxics [online]. 2023. Bd. 11 (2023), Heft 819. DOI 10.60810/openumwelt-186. Verfügbar unter: https://openumwelt.de/handle/123456789/1570
Zusammenfassung englisch
Human biomonitoring (HBM) data in Europe are often fragmented and collected in different EU countries and sampling periods. Exposure levels for children and adult women in Europe were evaluated over time. For the period 2000-2010, literature and aggregated data were collected in a harmonized way across studies. Between 2011-2012, biobanked samples from the DEMOCOPHES project were used. For 2014-2021, HBM data were generated within the HBM4EU Aligned Studies. Time patterns on internal exposure were evaluated visually and statistically using the 50th and 90th percentiles (P50/P90) for phthalates/DINCH and organophosphorus flame retardants (OPFRs) in children (5-12 years), and cadmium, bisphenols and polycyclic aromatic hydrocarbons (PAHs) in women (24-52 years). Restricted phthalate metabolites show decreasing patterns for children. Phthalate substitute, DINCH, shows a non-significant increasing pattern. For OPFRs, no trends were statistically significant. For women, BPA shows a clear decreasing pattern, while substitutes BPF and BPS show an increasing pattern coinciding with the BPA restrictions introduced. No clear patterns are observed for PAHs or cadmium. Although the causal relations were not studied as such, exposure levels to chemicals restricted at EU level visually decreased, while the levels for some of their substitutes increased. The results support policy efficacy monitoring and the policy-supportive role played by HBM. © 2023 by the authors