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The European human biomonitoring platform - Design and implementation of a laboratory quality assurance/quality control (QA/QC) programme for selected priority chemicals

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dc.contributor.authorLopéz, Marta Esteban
dc.contributor.authorGöen, Thomas
dc.contributor.authorKolossa-Gehring, Marike
dc.contributor.authorMol, Hans
dc.date.accessioned2024-06-16T13:38:18Z
dc.date.available2024-06-16T13:38:18Z
dc.date.issued2021
dc.description.abstractA fundamental objective of the human biomonitoring for Europe initiative (HBM4EU) is to progress toward comparable and robust exposure data for a wide variety of prioritized chemicals in human samples. A programme for Quality Assurance/Quality Control (QA/QC) was designed in HBM4EU with the purpose of creating a network of European laboratories providing comparable analytical data of high quality. Two approaches were chosen for two sets of prioritized chemicals with different timelines: (i) Scheme 1, where interested candidate laboratories participated in multiple rounds of proficiency tests (ii) Scheme 2, where selected expert laboratories participated in three rounds of interlaboratory comparison investigations. In both cases, the results were used to identify laboratories capable of generating consistent and comparable results for sample analysis in the frame of HBM4EU. In total, 84 laboratories from 26 countries were invited to participate in Scheme 1 that covered up to 73 biomarkers from Hexamoll® DINCH, phthalates, bisphenols, per- and polyfluoroalkyl substances, halogenated flame retardants (HFRs), organophosporous flame retardants (OPFRs), polycyclic aromatic hydrocarbons (PAH), cadmium, chromium and aromatic amines. 74 of the participants were successful for at least one biomarker in Scheme 1. Scheme 2 involved 22 biomarkers and successful results were obtained by 2 expert laboratories for arsenic, 5 for acrylamide, 4 for mycotoxins, 2 for pesticides and 2 for UV-filters in skin care products. The QA/QC programme allowed the identification of major difficulties and needs in HBM analysis as well of gaining insight in the analytical capacities of European laboratories. Furthermore, it is the first step towards the establishment of a sustainable European network of HBM laboratories. © 2021 The Authorsen
dc.format.extent1 Onlineresource (9 pages)
dc.format.mediumonline resource
dc.identifier.doihttps://doi.org/10.60810/openumwelt-122
dc.identifier.urihttps://openumwelt.de/handle/123456789/3438
dc.language.isoeng
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/
dc.titleThe European human biomonitoring platform - Design and implementation of a laboratory quality assurance/quality control (QA/QC) programme for selected priority chemicals
dc.title.alternativeThe European human biomonitoring platform - Design and implementation of a laboratory quality assurance/quality control (QA/QC) programme for selected priority chemicals
dc.typeWissenschaftlicher Artikel
dc.type.dcmitext
dc.type.mediumcomputer
dspace.entity.typePublication
local.bibliographicCitation.journalTitleInternational Journal of Hygiene and Environmental Health
local.bibliographicCitation.originalDOI10.1016/j.ijheh.2021.113740
local.bibliographicCitation.volume234 (2021)
local.collectionAufsätze
local.contributor.authorId02187880
local.contributor.authorId00341773
local.contributor.authorId02084723
local.identifier.catalogId02484668
local.ingest.leader05491naa a2200000uu 4500
local.jointTitleTHE EUROPEAN HUMAN BIOMONITORING PLATFORM DESIGN AND IMPLEMENTATION OF A LABORATORY QUALITY ASSURANCEQUALITY CONTROL QAQC PROGRAMME FOR SELECTED PRIORITY CHEMICALS
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