Publikation:
Management of patients with seasonal allergic rhinitis: Diagnostic consideration of sensitization to non-frequent pollen allergens

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dc.contributor.authorBalakirski, Galina
dc.contributor.authorHajdu, Zuzanna
dc.contributor.authorHöflich, Conny
dc.contributor.authorMücke, Hans-Guido
dc.contributor.authorStraff, Wolfgang
dc.date.accessioned2024-06-16T13:30:57Z
dc.date.available2024-06-16T13:30:57Z
dc.date.issued2021
dc.description.abstractBackground Diagnosis of pollen allergies is mainly based on test allergens for skin prick testing. In the minimum battery of test inhalant allergens recommended by the Global Allergy and Asthma European Network 10 pollen allergens are included. Complementary other pollen allergens may need to be considered; however, respective awareness may not always be granted. Furthermore, at least in Germany, the situation may be even more complicated by the fact that test allergens need regulatory approval. A decline in commercially available test allergens may result in a diagnostic gap regarding patients with non-frequent allergies. How many patients with non-frequent pollen allergies would be affected by this gap? The data presented here partly answer this question. Methods The study consisted of a descriptive and an analytical part. In the descriptive part, sensitization to frequent pollen allergens (alder, hazel, birch, sweet grasses; according to the German Therapy Allergen Ordinance) and to respective non-frequent pollen allergens (cypress, Japanese cedar, ash, plane tree, olive, Bermuda grass, wall pellitory, plantain, goosefoot, mugwort, ragweed, and saltwort) was measured in adult patients with physician-diagnosed allergic rhinitis from two German federal states, namely North-Rhine Westphalia (n = 360) and Bavaria (n = 339), using skin prick testing and/or ISAC technology. Furthermore, respective regional pollen data were assessed. In the analytical part, sensitization data were correlated with each other and with anamnestic data on symptom periods. Results Sensitization to frequent pollen allergens ranged from 45% (sIgE to Aln g 1/Alder, NRW) to 72% (prick test reactivity to birch, NRW). Sensitization to non-frequent pollen allergens ranged from 0% (sIgE to Amb a 1/ragweed, NRW) to 41% (prick test reactivity to olive, Bavaria). Sensitization data partly correlated with each other and in connection with symptom periods showed a partly similar seasonal pattern as pollen data. Conclusions Sensitization to non-frequent pollen allergens have to be considered when examining patients with respective seasonal symptoms, and test (and respective therapy) allergens for non-frequent pollen allergies need to be available. Further prerequisites for adequate patient management would be a nationwide pollen monitoring system giving continuous pollen data and a systematic sensitization monitoring at patient level. © The Authors.en
dc.format.mediumonline resource
dc.identifier.doihttps://doi.org/10.60810/openumwelt-86
dc.identifier.urihttps://openumwelt.de/handle/123456789/3190
dc.language.isoeng
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/
dc.subjectAllergie
dc.subjectPollen
dc.subjectMonitoring
dc.titleManagement of patients with seasonal allergic rhinitis: Diagnostic consideration of sensitization to non-frequent pollen allergens
dc.typeWissenschaftlicher Artikel
dc.type.dcmitext
dc.type.mediumcomputer
dspace.entity.typePublication
local.bibliographicCitation.journalTitleClinical and translational allergy
local.bibliographicCitation.originalDOI10.1002/clt2.12058
local.bibliographicCitation.volume11 (2021), Heft 8 vom 4.10.2021, 1 Onlineressource (11 Seiten)
local.collectionAufsätze
local.contributor.authorId(DE-588)124810187
local.contributor.authorId(DE-588)1025798783
local.contributor.authorId02173800
local.contributor.authorId02173801
local.identifier.catalogId02487194
local.ingest.leader06416naa a2200000uu 4500
local.jointTitleMANAGEMENT OF PATIENTS WITH SEASONAL ALLERGIC RHINITIS DIAGNOSTIC CONSIDERATION OF SENSITIZATION TO NONFREQUENT POLLEN ALLERGENS
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relation.isAuthorOfPublication.latestForDiscovery13e785d1-30b8-4927-8ffd-5d4f336f0093
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