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Frische, Tobias

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  • Veröffentlichung
    Widening the European Green Deal's perspective towards a sustainable Europe
    (Umweltbundesamt, 2021) Neßhöver, Carsten; Bannick, Claus Gerhard; Beckert, Barbara; Claussen, Ulrich; Doyle, Ulrike; Eckermann, Frauke; Frische, Tobias; Haße, Clemens; Günther, Jens; Hollweg, Beate; Huckestein, Burkhard; Janitzek, Timmo; Kabel, Claudia; Jering, Almut; Keßler, Hermann; Klatt, Anne; Knoche, Guido; Köder, Lea; Koller, Matthias; Krause, Bernd; Kreuser, Margarethe; Lindenthal, Alexandra; Löwe, Christian; Manstein, Christopher; Matthey, Astrid; Meurer, Doris; Mohaupt, Volker; Mutert, Tina; Obermaier, Nathan; Pieper, Silvia; Plickert, Sebastian; Rechenberg, Jörg; Reichart, Almut; Rönnefahrt, Ines; Schulte, Christoph; Schweitzer, Christian; Spengler, Laura; Stolzenberg, Hans-Christian; Suhr, Michael; Töpfer, Christoph; Unnerstall, Herwig; Deutschland. Umweltbundesamt
    The European Green Deal, published by the European Commission in 2019, represents a new and ambitious approach to put environment and sustainability at the heart of European policy. Its ambitions are high, yet the planned measures might not be sufficient to actually meet them. The report analyzes the European Green Deal from the perspective of the German Environment Agency and places it in the context of the global challenge of achieving the United Nations' sustainable development goals. In addition to necessary measures in the thematic fields of the European Green Deal, the report also addresses the structural adjustments needed as key levers to achieve the desired goals. The report concludes that the European Green Deal is an important step forward, but that further efforts beyond those described there are still needed in order to achieve a sustainable Europe. Quelle: www.umweltbundesamt.de
  • Veröffentlichung
    Better define beta-optimizing MDD (minimum detectable difference) when interpreting treatment-related effects of pesticides in semi-field and field studies
    (2020) Alalouni, Urwa; Duquesne, Sabine; Egerer, Sina Elisabeth; Frische, Tobias; Gergs, René; Gräff, Thomas; Sahm, René; Pieper, Silvia; Wogram, Jörn
    The minimum detectable difference (MDD) is a measure of the difference between the means of a treatment and the control that must exist to detect a statistically significant effect. It is a measure at a defined level of probability and a given variability of the data. It provides an indication for the robustness of statistically derived effect thresholds such as the lowest observed effect concentration (LOEC) and the no observed effect concentration (NOEC) when interpreting treatment-related effects on a population exposed to chemicals in semi-field studies (e.g., micro-/mesocosm studies) or field studies. MDD has been proposed in the guidance on tiered risk assessment for plant protection products in edge of field surface waters (EFSA Journal 11(7):3290, 2013), in order to better estimate the robustness of endpoints from such studies for taking regulatory decisions. However, the MDD calculation method as suggested in this framework does not clearly specify the power which is represented by the beta-value (i.e., the level of probability of type II error). This has implications for the interpretation of experimental results, i.e., the derivation of robust effect values and their use in risk assessment of PPPs. In this paper, different methods of MDD calculations are investigated, with an emphasis on their pre-defined levels of type II error-probability. Furthermore, a modification is suggested for an optimal use of the MDD, which ensures a high degree of certainty for decision-makers. © 2020 Springer Nature Switzerland AG