Auflistung nach Autor:in "Brandt, Ute"
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Veröffentlichung Comparing pharmaceutical persistence across terrestrial and aquatic environments: do studies according to OECD 307 and OECD 308 lead to similar outcomes?(2023) Berkner, Silvia; Brandt, UteInformation on transformation and persistence of chemical substances in the environment is important for hazard and risk assessment within a regulatory context or as a decision criterion in a safe and sustainable by design framework. Half-lives for human and veterinary medicinal products available from marketing authorization applications were compared between soil (OECD 307) and aquatic water/sediment systems (OECD 308). The comparison shows, that there is no obvious correlation between the total system half-lives in the two different compartments and that surpassing persistence criteria is compartment-specific in 45% of the cases. © The Author(s) 2023Veröffentlichung Human pharmaceutical substances(2022) Gildemeister, Daniela; Hein, Arne; Brandt, Ute; Buck, Annika; Hickmann, Silke; Rönnefahrt, Ines