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Auflistung Vorträge/Reden nach Autor:in "Apel, Gerda"

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    Analysis of new chemicals in the 5th German Environmental Survey 2014-2017
    (2015) Kolossa-Gehring, Marike; Schwedler, Gerda; Apel, Gerda; Koch, Holger Martin; Seiwert, Margarete; Conrad, André; Schulz, Christine; Fiddicke, Ulrike
    The German Environmental Surveys (GerES) are large scale population studies repeatedly been carried out since the mid-1980s. GerES evaluates pollutant body burdens in population-representative samples, the contribution of different media (air, drinking water, food) to the overall exposure, and links human biomonitoring (HBM) to health data. GerES is conducted in cooperation with the National Health Interview and Examination Surveys (NHIES) performed by the Robert Koch Institute. GerES V focuses on emerging substances with potential health relevance and/or assumed exposure of the general population (e.g. plasticizer alternatives like Hexamoll® DINCH and di-2-propylheptyl phthalate (DPHP), the solvents N-methyl- and N-ethyl-2-pyrrolidone (NMP/NEP), 6 parabens, Triclosan and the vulcanization accelerator 2-mercaptobenzothiazole (2-MBT)) which are measured in children and adolescents aged 3 to 17 years. A pilot study (n=39) was conducted in 2013 to validate instruments and field work procedures. GerES V field work started in 2014. The pilot study revealed large differences in exposure between chemicals and individuals. The percent of samples with markers above LOQ were: 100% for DEHP and DINCH, 97% for NEP and NMP, 55% for DPHP, 30% for Triclosan, 28% for 2-MBT and between 100% and 3% for different parabens. Maximum levels for methylparaben and N-propylparaben were 6.8 and 3.4 mg/l urine, respectively, applying a method with a LOQ of 0.5 ìg/l. All values were below the established or proposed Human Biomonitoring values of the German HBM Commission for DEHP, DINCH, DPHP, NEP, NMP and 2-MBT. However, only the main study supplies population representative data which can answer the question if subgroups might be exposed to critical levels as judged by a toxicological assessment of single or combined effects. GerES is funded by the Federal Ministry for the Environment, Nature Conservation, Building and Nuclear Safety (BMUB) and the Federal Ministry of Education and Research.In: 25th Annual Meeting: Exposures in an Evolving Environment: October 18 - 22, 2015 - Henderson, Nevada: final Abstract Book. International Societyof Exposure Science. Henderson,S.124