Person: Neumann, Michael
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Veröffentlichung Assessment of persistence, mobility and toxicity (PMT) of 167 REACH registered substances(2018) Berger, Urs; Ost, Norbert; Neumann, Michael; Sättler, Daniel; Schliebner, Ivo; Helmholtz-Zentrum für Umweltforschung; Deutschland. UmweltbundesamtFor the first time a comprehensive list of 167 REACH registered substances were assessed with respect to their intrinsic substance properties persistence in the aquatic environment, mobility in the aquatic environment and toxicity. The results of this project will support the ongoing discussion to define PMT criteria under REACH. The present study provides a consolidated list of (in order of priority) assessed PaqMT substances (9 substances), assessed PaqM substances with suspected T (20 substances) and further 93 suspected PaqMT substances. A total of 134 substances are recommended to the German Environment Agency (UBA) for further investigation and scientific and regulatory scrutiny.Veröffentlichung The NORMAN Suspect List Exchange (NORMAN-SLE): facilitating European and worldwide collaboration on suspect screening in high resolution mass spectrometry(2022) Taha, Hiba Mohammed; Aalizadeh, Reza; Alygizakis, Nikiforos A.; Koschorreck, Jan; Meier, Christiane; Neumann, Michael; Schliebner, Ivo; von der Ohe, Peter C.Background The NORMAN Association (https://www.norman-network.com/) initiated the NORMAN Suspect List Exchange (NORMAN-SLE; https://www.norman-network.com/nds/SLE/) in 2015, following the NORMAN collaborative trial on non-target screening of environmental water samples by mass spectrometry. Since then, this exchange of information on chemicals that are expected to occur in the environment, along with the accompanying expert knowledge and references, has become a valuable knowledge base for "suspect screening" lists. The NORMAN-SLE now serves as a FAIR (Findable, Accessible, Interoperable, Reusable) chemical information resource worldwide. Results The NORMAN-SLE contains 99 separate suspect list collections (as of May 2022) from over 70 contributors around the world, totalling over 100,000 unique substances. The substance classes include per- and polyfluoroalkyl substances (PFAS), pharmaceuticals, pesticides, natural toxins, high production volume substances covered under the European REACH regulation (EC: 1272/2008), priority contaminants of emerging concern (CECs) and regulatory lists from NORMAN partners. Several lists focus on transformation products (TPs) and complex features detected in the environment with various levels of provenance and structural information. Each list is available for separate download. The merged, curated collection is also available as the NORMAN Substance Database (NORMAN SusDat). Both the NORMAN-SLE and NORMAN SusDat are integrated within the NORMAN Database System (NDS). The individual NORMAN-SLE lists receive digital object identifiers (DOIs) and traceable versioning via a Zenodo community (https://zenodo.org/communities/norman-sle), with a total of > 40,000 unique views, > 50,000 unique downloads and 40 citations (May 2022). NORMAN-SLE content is progressively integrated into large open chemical databases such as PubChem (https://pubchem.ncbi.nlm.nih.gov/) and the US EPA's CompTox Chemicals Dashboard (https://comptox.epa.gov/dashboard/), enabling further access to these lists, along with the additional functionality and calculated properties these resources offer. PubChem has also integrated significant annotation content from the NORMAN-SLE, including a classification browser (https://pubchem.ncbi.nlm.nih.gov/classification/#hid=101). Conclusions The NORMAN-SLE offers a specialized service for hosting suspect screening lists of relevance for the environmental community in an open, FAIR manner that allows integration with other major chemical resources. These efforts foster the exchange of information between scientists and regulators, supporting the paradigm shift to the "one substance, one assessment" approach. New submissions are welcome via the contacts provided on the NORMAN-SLE website (https://www.norman-network.com/nds/SLE/). © The Authors 2022Veröffentlichung Protecting the sources of our drinking water(Umweltbundesamt, 2019) Neumann, Michael; Schliebner, Ivo; Deutschland. UmweltbundesamtChemicals with a specific combination of intrinsic substance properties pose a hazard to the sources of our drinking water, including substances that are very persistent (vP) in the environment and very mobile (vM) in the aquatic environment as well as substances that are persistent (P), mobile (M), and toxic (T). This publication presents the result of the scientific and technical development of the PMT/vPvM criteria under EU REACHRegulation (EC) No 1907/2006. The scientific and regulatory considerations include (1) monitoring data, (2) simulation and model studies and (3) impact considerations. This can be considered a ready-to-use tool for industry to identify PMT/vPvM substances. Quelle: http://www.umweltbundesamt.de/Veröffentlichung Protecting the sources of our drinking water(2017) Neumann, Michael; Schliebner, Ivo; Deutschland. UmweltbundesamtProtecting the sources of our drinking water from any threats caused by chemicals is of the utmost importance. A strategy is needed in order to allow Europe̷s chemical industry to continue to innovate while ensuring the protection of the water cycle. The German Environment Agency (UBA) is carrying out an initiative to identify those substances that are persistent (P) in the environment, mobile (M) in the water cycle (PM substances), and additionally toxicity (T) to human health (PMT substances). The proposed criteria will assist registrants in fulfilling their responsibility of guaranteeing the safe use of chemicals under the EU̷s chemical regulation ̮REACHŁ (Regulation EC No 1907/2006). Quelle: https://www.umweltbundesamt.de/Veröffentlichung Prioritised PMT/vPvM substances in the REACH registration database(Umweltundesamt, 2023) Arp, Hans Peter; Hale, Sarah E.; Neumann, Michael; Schliebner, IvoDie aktualisierte UBA-Liste mit 343 PMT/vPvM-Stoffen (einzigartige chemische Strukturen), die zu 474 registrierten Stoffen in der REACH-Registrierungsdatenbank gehören, wird präsentiert. Dies ist die erste Aktualisierung der UBA-Liste mit PMT/vPvM-Stoffen Stand Mai 2017, die ursprünglich als UBA TEXTE 126/2019 veröffentlicht wurde. Dieses Update basiert auf der REACH-Registrierungsdatenbank Stand September 2019. Die UBA-Liste ist in drei Prioritätskategorien unterteilt, je nachdem, ob das Registrierungsvolumen > 10 tpa beträgt und ob der Stoff derzeit in Europa reguliert ist. Die höchste Prioritätskategorie A umfasst 173 PMT/vPvM-Stoffe. Die beiden mittleren Prioritätskategorien B und C umfassen 142 bzw. 29 PMT/vPvM-Stoffe. Von diesen 343 PMT/vPvM-Stoffen erfüllen nur 259 Stoffe die weniger strengen PMT/vPvM Kriterien, die die Europäische Kommission 2021 für neue Gefahrenklassen im Rahmen der CLP Verordnung vorgeschlagen hat. Es werden weitere 421 einzigartige chemische Strukturen (die zu 474 registrierten Stoffen gehören) präsentiert, die als persistent und mobil eingestuft wurden, aber derzeit keine qualitativ hochwertigen Konsensfolgerungen haben, dass das Toxizitätskriterium erfüllt ist. Die priorisierte UBA-Liste mit 343 PMT/vPvM-Stoffen in der REACH-Registrierungsdatenbank ist für Registranten und nachgeschaltete Anwender direkt nutzbar. Sie können sofort handeln, um Emissionen während des gesamten Lebenszyklus ihrer Stoffe zu reduzieren und zu minimieren, um letztlich die Sicherheit der Trinkwasserressourcen zu erhöhen und die aquatische Umwelt für zukünftige Generationen zu schützen. Quelle: Forschungsbericht