Person: Eckhardt, Alexander
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Veröffentlichung Limit Values and Guideline Values in Regulatory Toxicology(2014) Heine, Karin; Eckhardt, AlexanderDepending on thematrix (e.g.,water, air) and the classification of a substance (e.g.,contaminant), a multitude of limits and guidelines has been defined. The motivationfor defining such a limit or guideline can be different. The most importantreason is to protect the population fromadverse health effects such as acute chronictoxicity or cancer. Another reason could be the protection of ecosystems whichcould be more vulnerable than humans. Moreover, aesthetic considerations, likethe taste and/or odor of drinking water, can result in limitations of chemicals. Inthe following chapter, definitions of and examples for limits in water, air, oroccupational environments are given. These lists are by no means exhaustible.© Springer-Verlag Berlin Heidelberg 2014Veröffentlichung Kupfer im Trinkwasser(2016) Dieter, Hermann H.; Eckhardt, AlexanderVeröffentlichung Bor im Trinkwasser(2016) Eckhardt, AlexanderVeröffentlichung Sensitive Humans Versus Average Persons in Toxicology(2014) Eckhardt, AlexanderThe sensitivity of human beings against toxic insults or pharmaceuticals variesconsiderably. This fact has various reasons, e.g., health status, age, body weight,as well as genetic background. An increased sensitivity against a noxious substancecan have severe or even lethal consequences. Therefore, it is compulsoryfor toxicologists to take these differences into account when establishing limitsfor toxic compounds. ©Springer-Verlag Berlin Heidelberg 2014Veröffentlichung Schlussbericht des RiSKWa-Verbundprojekts TOX-BOX: "Gefährdungsbasiertes Risikomanagement für anthropogene Spurenstoffe zur Sicherung der Trinkwasserversorgung"(2016) Eckhardt, Alexander; Grummt, Tamara; Heinze, RitaVeröffentlichung Positive trends emerge in reducing exposure to 1,4-dioxane(2018) Eckhardt, AlexanderAlthough there are challenges in monitoring and treating 1,4-dioxane, there is also a significant decrease in the use of this contaminant, which points to reduced concentrations in both air and water.