Person: Sättler, Daniel
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Veröffentlichung Assessment of persistence, mobility and toxicity (PMT) of 167 REACH registered substances(2018) Berger, Urs; Ost, Norbert; Neumann, Michael; Sättler, Daniel; Schliebner, Ivo; Helmholtz-Zentrum für Umweltforschung; Deutschland. UmweltbundesamtFor the first time a comprehensive list of 167 REACH registered substances were assessed with respect to their intrinsic substance properties persistence in the aquatic environment, mobility in the aquatic environment and toxicity. The results of this project will support the ongoing discussion to define PMT criteria under REACH. The present study provides a consolidated list of (in order of priority) assessed PaqMT substances (9 substances), assessed PaqM substances with suspected T (20 substances) and further 93 suspected PaqMT substances. A total of 134 substances are recommended to the German Environment Agency (UBA) for further investigation and scientific and regulatory scrutiny.Veröffentlichung A weight-of-evidence approach to assess chemicals: case study on the assessment of persistence of 4,6-substituted phenolic benzotriazoles in the environment(2016) Becker, Eva; Brandt, Marc; Jöhncke, Ulrich; Sättler, Daniel; Schulte, ChristophBackground
One important purpose of the European REACH Regulation (EC No. 1907/2006) is to promote the use of alternative methods for assessment of hazards of substances in order to avoid animal testing. Experience with environmental hazard assessment under REACH shows that efficient alternative methods are needed in order to assess chemicals when standard test data are missing. One such assessment method is the weight-of-evidence (WoE) approach. In this study, the WoE approach was used to assess the persistence of certain phenolic benzotriazoles, a group of substances including also such of very high concern (SVHC).
Results
For phenolic benzotriazoles, assessment of the environmental persistence is challenging as standard information, i.e. simulation tests on biodegradation are not available. Thus, the WoE approach was used: overall information resulting from many sources was considered, and individual uncertainties of each source analysed separately. In a second step, all information was aggregated giving an overall picture of persistence to assess the degradability of the phenolic benzotriazoles under consideration although the reliability of individual sources was incomplete.
Conclusions
Overall, the evidence suggesting that phenolic benzotriazoles are very persistent in the environment is unambiguous. This was demonstrated by a WoE approach considering the prerequisites of REACH by combining several limited information sources. The combination enabled a clear overall assessment which can be reliably used for SVHC identification. Finally, it is recommended to include WoE approaches as an important tool in future environmental risk assessments.
Quelle: https://enveurope.springeropen.com