Person: Höflich, Conny
Lade...
E-Mail-Adresse
Geburtsdatum
Forschungsvorhaben
Organisationseinheiten
Berufsbeschreibung
Nachname
Höflich
Vorname
Conny
Name
4 Ergebnisse
Suchergebnisse
Gerade angezeigt 1 - 4 von 4
Veröffentlichung Management of patients with seasonal allergic rhinitis: Diagnostic consideration of sensitization to non-frequent pollen allergens(2021) Balakirski, Galina; Hajdu, Zuzanna; Höflich, Conny; Mücke, Hans-Guido; Straff, WolfgangBackground Diagnosis of pollen allergies is mainly based on test allergens for skin prick testing. In the minimum battery of test inhalant allergens recommended by the Global Allergy and Asthma European Network 10 pollen allergens are included. Complementary other pollen allergens may need to be considered; however, respective awareness may not always be granted. Furthermore, at least in Germany, the situation may be even more complicated by the fact that test allergens need regulatory approval. A decline in commercially available test allergens may result in a diagnostic gap regarding patients with non-frequent allergies. How many patients with non-frequent pollen allergies would be affected by this gap? The data presented here partly answer this question. Methods The study consisted of a descriptive and an analytical part. In the descriptive part, sensitization to frequent pollen allergens (alder, hazel, birch, sweet grasses; according to the German Therapy Allergen Ordinance) and to respective non-frequent pollen allergens (cypress, Japanese cedar, ash, plane tree, olive, Bermuda grass, wall pellitory, plantain, goosefoot, mugwort, ragweed, and saltwort) was measured in adult patients with physician-diagnosed allergic rhinitis from two German federal states, namely North-Rhine Westphalia (n = 360) and Bavaria (n = 339), using skin prick testing and/or ISAC technology. Furthermore, respective regional pollen data were assessed. In the analytical part, sensitization data were correlated with each other and with anamnestic data on symptom periods. Results Sensitization to frequent pollen allergens ranged from 45% (sIgE to Aln g 1/Alder, NRW) to 72% (prick test reactivity to birch, NRW). Sensitization to non-frequent pollen allergens ranged from 0% (sIgE to Amb a 1/ragweed, NRW) to 41% (prick test reactivity to olive, Bavaria). Sensitization data partly correlated with each other and in connection with symptom periods showed a partly similar seasonal pattern as pollen data. Conclusions Sensitization to non-frequent pollen allergens have to be considered when examining patients with respective seasonal symptoms, and test (and respective therapy) allergens for non-frequent pollen allergies need to be available. Further prerequisites for adequate patient management would be a nationwide pollen monitoring system giving continuous pollen data and a systematic sensitization monitoring at patient level. © The Authors.Veröffentlichung Management of patients with seasonal allergic rhinitis: Diagnostic consideration of sensitization to non-frequent pollen allergens(2021) Balakirski, Galina; Höflich, Conny; Mücke, Hans-Guido; Straff, WolfgangVeröffentlichung Management of patients with seasonal allergic rhinitis: diagnostic consideration of sensitization to non-frequent pollen allergens(2022) Balakirski, Galina; Höflich, Conny; Mücke, Hans-Guido; Straff, Wolfgang; Deutschland. Umweltbundesamt. Fachbereich II - Gesundheitlicher Umweltschutz, Schutz der ÖkosystemeBackground Diagnosis of pollen allergies is mainly based on test allergens for skin prick testing. In the minimum battery of test inhalant allergens recommended by the Global Allergy and Asthma European Network ten pollen allergens are included. Complementary, other pollen allergens may need to be considered, however, respective awareness may not always be granted. Furthermore, at least in Germany, the situation may be even more complicated by the fact that test allergens need regulatory approval. A decline of commercially available test allergens may result in a diagnostic gap regarding patients with non-frequent allergies. How many patients with non-frequent pollen allergies would be affected by this gap? The data presented here partly answer this question. Method The study consisted of a descriptive and an analytical part. In the descriptive part, sensitization to frequent pollen allergens (alder, hazel, birch, sweet grasses; according to the German Therapy Allergen Ordinance) and to respective non-frequent pollen allergens (cypress, Japanese cedar, ash, plane tree, olive, Bermuda grass, wall pellitory, plantain, goosefoot, mugwort, ragweed and saltwort) were measured in adult patients with physician-diagnosed allergic rhinitis from two German federal states, namely North-Rhine Westphalia (n=360) and Bavaria (n=339), using skin prick testing and/or ISAC technology. Furthermore, respective regional pollen data were assessed. In the analytical part, sensitization data were correlated with each other and with anamnestic data on symptom periods. Results Sensitization to frequent pollen allergens ranged from 45 % (sIgE to Aln g 1/alder, NRW) to 72 % (prick test reactivity to birch, NRW). Sensitization to non-frequent pollen allergens ranged from 0 % (sIgE to Amb a 1/ragweed, NRW) to 41 % (prick test reactivity to olive, Bavaria). Sensitization data partly correlated with each other and in connection with symptom periods showed a partly similar seasonal pattern as pollen data. Conclusion Sensitization to non-frequent pollen allergens have to be considered when examining patients with respective seasonal symptoms, and test (and respective therapy) allergens for non-frequent pollen allergies need to be available. Further prerequisites for adequate patient management would be a nationwide pollen monitoring system giving continuous pollen data and a systematic sensitization monitoring at patient level. Quelle: www.eaaci2022.process.y-congress.comVeröffentlichung Management von Patienten und Patientinnen mit saisonaler allergischer Rhinitis(2023) Balakirski, Galina; Hajdu, Zuzanna; Höflich, Conny; Mücke, Hans-Guido; Straff, WolfgangEin wichtiges Instrument in der Diagnostik von Pollenallergien sind Haut-Pricktestungen mittels Testallergenen. In der vom Global Allergy and Asthma European Network für Europa empfohlenen Mindesttestreihe sind zehn Pollenallergene enthalten. Ergänzend dazu müssen in konkreten Fällen unter Umständen weitere Pollenallergene berücksichtigt werden, aber nicht immer kann von den diesbezüglich erforderlichen Kenntnissen ausgegangen werden. Für Deutschland stellt sich die Situation noch schwieriger dar, weil Testallergene hier einer behördlichen Zulassung bedürfen. Ein Rückgang kommerziell erhältlicher Testallergene kann zu einer diagnostischen Lücke bei Patienten und Patientinnen mit seltenen Allergien führen. Wie viele Patienten und Patientinnen mit weniger häufigen und seltenen Pollenallergien wären von dieser Lücke betroffen? Die hier gezeigten Daten beantworten diese Frage teilweise. Quelle: UMID : Umwelt und Mensch - Informationsdienst ; Umwelt & Gesundheit, Umweltmedizin, Verbraucherschutz / Boden- und Lufthygiene (Berlin) Institut für Wasser- - (2023), Heft 1, Seite 67