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Kolossa-Gehring, Marike

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Kolossa-Gehring
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Marike
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  • Veröffentlichung
    HBM4EU feasibility studies: Lessons learned in combining health and human biomonitoring studies
    (2023) Elonheimo, Hanna; David, Madlen; Uusitalo, Karoliina; Moore, Sonja; Kolossa-Gehring, Marike
    Background: The European Human Biomonitoring Initiative (HBM4EU) is a joint program evaluating humans-exposure to several environmental substances and their potential health effects. One of the main objectives ofHBM4EU is to make use of human biomonitoring (HBM) to assess human exposure to chemicals in Europe tobetter understand the associated health impacts and to improve chemical risk assessment. In parallel to HBMstudies, health examination surveys (HESs), nutrition/dietary surveys, and disease specific health surveys areconducted in many European countries. In HESs, information collected by questionnaire(s) is supplemented withphysical examinations and analysis of clinical and biological biomarkers in biological samples. HBM and healthexamination survey (HES) use similar data collection methods and infrastructures hence the feasibility ofcombining these two is explored in this paper. Methods: Within HBM4EU, three feasibility studies (in Finland, Germany, and UK/England) were conducted toevaluate opportunities and obstacles of combining HBM and health studies. In this paper we report lessonslearned from these feasibility studies. Results: The Finnish feasibility study called KouBio-KUOPIO study was a new initiative without links to existingstudies. The German feasibility study added a HBM module to the first follow-up examination of the LIFE-Adult-Study, a population-based cohort study. The UK feasibility integrates a sustainable HBM module into the HealthSurvey for England (HSfE), an annual health examination survey. Benefits of combining HBM and HESs includethe use of shared infrastructures. Furthermore, participants can receive additional health information from HES,and participation rates tend to be higher due to the potential to obtain personal health information. Preparatoryphases including obtaining ethical approval can be time-consuming and complicated. Recruitment of participantsand low participation rates are common concerns in survey research and therefore designing user-friendly. 2022 The Authors